Pediatric cardiopulmonary resuscitation: advances in science, techniques, and outcomes.
Pediatric cardiopulmonary resuscitation: advances in science, techniques, and outcomes.
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DOI：
10.1542/peds.2007-3313
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发表时间：
2008-11
期刊：
影响因子：
8
通讯作者：
Nadkarni VM
中科院分区：
文献类型：
--
作者：
Topjian AA;Berg RA;Nadkarni VM
超过25%的儿童在院内心脏骤停后存活至出院，5%至10%的儿童在院外心脏骤停后存活。本文综述了小儿心脏骤停的流行病学、心肺复苏过程中冠状动脉血流的机制、心脏骤停复苏的4个阶段、每个阶段的适当干预、特殊复苏情况、体外膜肺氧合心肺复苏和心肺复苏质量。病理生理学的关键要素，影响和匹配的时间，强度，持续时间和变化的缺氧缺血性损伤的循证干预措施进行审查。基础和应用科学实验室的令人兴奋的发现现在与儿科心脏骤停受害者和情况的特定亚群相关（例如，室颤，新生儿，先天性心脏病，体外心肺复苏）。人们日益认识到，提高干预措施的质量是改善成果的一个关键因素。不断发展的培训策略包括模拟培训，即时和即时培训，以及危机团队培训。解决了何时停止复苏努力的难题。小儿心脏骤停的预后正在改善。复苏科学的进步和最先进的实施技术为进一步改善儿童心脏骤停后的结局提供了机会。
More than 25% of children survive to hospital discharge after in-hospital cardiac arrests, and 5% to 10% survive after out-of-hospital cardiac arrests. This review of pediatric cardiopulmonary resuscitation addresses the epidemiology of pediatric cardiac arrests, mechanisms of coronary blood flow during cardiopulmonary resuscitation, the 4 phases of cardiac arrest resuscitation, appropriate interventions during each phase, special resuscitation circumstances, extracorporeal membrane oxygenation cardiopulmonary resuscitation, and quality of cardiopulmonary resuscitation. The key elements of pathophysiology that impact and match the timing, intensity, duration, and variability of the hypoxic-ischemic insult to evidence-based interventions are reviewed. Exciting discoveries in basic and applied-science laboratories are now relevant for specific subpopulations of pediatric cardiac arrest victims and circumstances (eg, ventricular fibrillation, neonates, congenital heart disease, extracorporeal cardiopulmonary resuscitation). Improving the quality of interventions is increasingly recognized as a key factor for improving outcomes. Evolving training strategies include simulation training, just-in-time and just-in-place training, and crisis-team training. The difficult issue of when to discontinue resuscitative efforts is addressed. Outcomes from pediatric cardiac arrests are improving. Advances in resuscitation science and state-of-the-art implementation techniques provide the opportunity for further improvement in outcomes among children after cardiac arrest.
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影响因子：
37.8
作者：
Aufderheide, TP;Sigurdsson, G;Lurie, KG
通讯作者：
Lurie, KG
影响因子：
8.8
作者：
BERKOWITZ, ID;GERVAIS, H;TRAYSTMAN, RJ
通讯作者：
TRAYSTMAN, RJ
影响因子：
6.5
作者：
Chamnanvanakij, S;Perlman, JM
通讯作者：
Perlman, JM
影响因子：
4.2
作者：
Conrad, SA;Rycus, PT;Dalton, H
通讯作者：
Dalton, H
影响因子：
158.5
作者：
BROWN, CG;MARTIN, DR;JASTREMSKI, M
通讯作者：
JASTREMSKI, M