Risk factors for suicide independent of DSM-III-R axis I disorder - Case-control psychological autopsy study in Northern Ireland

Risk factors for suicide independent of DSM-III-R axis I disorder - Case-control psychological autopsy study in Northern Ireland
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DOI:
10.1192/bjp.175.2.175
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发表时间:
1999-08-01
影响因子:
10.5
通讯作者:
Patterson, C
Patterson, C
中科院分区:
医学1区
文献类型:
--
作者:
Foster, T;Gillespie, K;Patterson, C

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背景绝大多数自杀者在死亡时至少患有一种精神障碍。目的是确定自杀的危险因素,特别是那些独立于当前DSM-III-R轴I障碍的因素。方法采用病例对照心理尸检研究,将自杀者与匹配的社区对照进行比较。结果自杀的独立危险因素包括:轴II人格障碍(特别是反社会,回避和依赖);至少12个生活事件之一(来自威胁经历列表)在过去52周或4周内(特别是“与亲密朋友,邻居或亲戚的严重问题”);目前失业;以前故意自残的历史;以及在26周内与全科医生接触。相对于目前没有精神障碍的个体,I轴-II轴共病患者的估计自杀风险(OR 346.0)显著高于轴I障碍组(OR 52.4)。结论通过对上述独立危险因素的调查,可以加强自杀风险评估,利益声明由卫生和社会服务部(北方爱尔兰)、西部卫生和社会服务委员会、Yews Trust的Samuel Scott爵士、Eli Lilly and Co. Ltd和Duphar Laboratories Ltd资助。
Background The vast majority of suicides suffer from at least one mental disorder at the time of death.Aims To identify risk factors for suicide, particularly those independent of current DSM-III-R Axis I disorder(s).Method A case-control psychological autopsy study comparing suicides with matched community controls.Results Independent risk factors for suicide included: Axis II (personality) disorder (particularly antisocial, avoidant and dependent); at least one of 12 life events (from the List of Threatening Experiences) during the previous 52 or 4 weeks (in particular, a 'serious problem with close friend, neighbour or relative'); current unemployment; previous history of deliberate self-harm; and contact with a GP within 26 weeks. Relative to individuals with no current mental disorder, the estimated risk of suicide in those with Axis I-Axis II comorbidity (OR 346.0) was significantly greater than that in those with Axis I disorder(s) only (OR 52.4).Conclusions Suicide risk assessment may be enhanced by enquiry about the aforementioned independent risk factors, and attention to Axis I-Axis II comorbidity.Declaration of interest Funded by Department of Health and Social Services (Northern Ireland),Western Health and Social Services Board, Sir Samuel Scott of Yews Trust, Eli Lilly and Co. Ltd and Duphar Laboratories Ltd.