SEQUENCE OF DNA-REPLICATION IN 277 R-BANDS AND Q-BANDS OF HUMAN-CHROMOSOMES USING A BRDU TREATMENT
SEQUENCE OF DNA-REPLICATION IN 277 R-BANDS AND Q-BANDS OF HUMAN-CHROMOSOMES USING A BRDU TREATMENT
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DOI：
10.1007/bf00293440
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发表时间：
1976-01-01
期刊：
影响因子：
1.6
通讯作者：
VIEGASPEQUIGNOT, E
中科院分区：
文献类型：
--
作者：
DUTRILLAUX, B;COUTURIER, J;VIEGASPEQUIGNOT, E
复制时间的所有重要的染色体带的类型R和Q（277个结构）进行了分析。R带形成一组结构，其DNA在早期S期复制，而位于Q带的DNA在晚期S期复制。这两种类型的结构的复制时间之间可能不存在重叠。最宽的R带是最早复制的那些;一般来说，最强的Q带是最晚复制的那些。特别是在最后这些中，在复制时间之间存在一定的不同步性。最后，1、16和Y染色体的异染色质以及端着丝粒短臂的异染色质可能含有两种类型的DNA，它们在不同的时间复制。
Replication times for all important chromosome bands of both types R and Q (277 structures) are analyzed. The R-bands form a group of structures whose DNA replicates during the early S-phase, while the DNA situated in the Q-bands replicates during the late S-phase. There may not exist overlapping between replication times of these 2 types of structures. The widest R-bands are those which are the earliest to replicate; in general, the most intense Q-bands are those which are the latest to replicate. Especially among these last ones, a certain asynochronism exists between the replication times. Finally the heterochromatin of chromosomes 1, 16 and Y and of the short arms of the acrocentrics could contain 2 types of DNA which replicate at different times.