Cytogenetic and molecular predictors of outcome in acute lymphocytic leukemia: recent developments.
Cytogenetic and molecular predictors of outcome in acute lymphocytic leukemia: recent developments.
复制标题
DOI:
10.1007/s11899-012-0122-5
复制
发表时间:
2012-06
影响因子:
2.9
通讯作者:
Martinelli, Giovanni
中科院分区:
文献类型:
--
作者:
Iacobucci, Ilaria;Papayannidis, Cristina;Lonetti, Annalisa;Ferrari, Anna;Baccarani, Michele;Martinelli, Giovanni
During the last decade a tremendous technologic progress based on genome-wide profiling of genetic aberrations, structural DNA alterations, and sequence variations has allowed a better understanding of the molecular basis of pediatric and adult B/T- acute lymphoblastic leukemia (ALL), contributing to a better recognition of the biological heterogeneity of ALL and to a more precise definition of risk factors. Importantly, these advances identified novel potential targets for therapeutic intervention. This review will be focused on the cytogenetic/molecular advances in pediatric and adult ALL based on recently published articles.
登录
查看更多内容
影响因子:
51.1
作者:
Den Boer, Monique L.;van Slegtenhorst, Marjon;De Menezes, Renee X.;Cheok, Meyling H.;Buijs-Gladdines, Jessica G. C. A. M.;Peters, Susan T. C. J. M.;Van Zutven, Laura C. M.;Beverloo, H. Berna;Van der Spek, Peter J.;Escherich, Gaby;Horstmann, Martin A.;Janka-Schoub, Gritta E.;Kamps, Willem A.;Evans, William E.;Pieters, Rob
通讯作者:
Pieters, Rob
影响因子:
82.9
作者:
通讯作者:
--
影响因子:
20.3
作者:
Gutierrez, Alejandro;Sanda, Takaomi;Look, A. Thomas
通讯作者:
Look, A. Thomas
影响因子:
--
作者:
Andreasson, P;Schwaller, J;Gilliland, DG
通讯作者:
Gilliland, DG
影响因子:
11.4
作者:
Clappier, E;Cuccuini, W;Soulier, J
通讯作者:
Soulier, J