Analysis of Radiography Findings of Ossification of Nuchal Ligament of Cervical Spine in Patients With Cervical Spondylosis-猫眼课题宝

DOI：

10.1097/brs.0000000000000037

发表时间：

2014-01

期刊：

Spine

影响因子：

通讯作者：

中科院分区：

医学2区

文献类型：

作者：

Hongli Wang;Fei Zou;Jianyuan Jiang;Feizhou Lu;Wen-jun Chen;Xiaosheng Ma;X. Xia;Li-xun Wang

研究设计。回顾性临床数据分析。客观的。本研究旨在探讨颈椎病患者颈韧带骨化症（ONL）的发生率、相关因素及影像学表现，为进一步研究ONL与颈椎病的关系奠定基础。背景数据摘要。颈项韧带损伤可能导致ONL，可能会加剧颈椎不稳定，导致颈椎病。因此，了解颈椎病患者ONL的特征非常重要。方法。回顾了 372 名颈椎病患者的病历。数据分析包括患者的性别、年龄、ONL 的位置和分类以及后纵韧带骨化 (OPLL)。通过横向平片和计算机断层扫描进行二维矢状面重建来评估放射学特征。结果。 372例颈椎病患者中，49.7%诊断为ONL； ONL的发病率男性高于女性（P = 0.001），老年患者高于年轻患者（P = 0.005）。平片上ONL的不同图像分为局部型、连续型、节段型、混合型和未分类5种类型，分布比例分别为49.7%、33.0%、3.2%、8.6%和5.4%。 ONL主要发生在C4,5（75.7%）和C5,6（81.1%）水平。 OPLL患者ONL的发生率高于其他患者（P < 0.001），OPLL患者多节段ONL的发生率高于单纯ONL患者（P = 0.038）。结论。颈椎病患者ONL的发生率为49.7%。性别、年龄、OPLL是ONL的相关因素。 ONL可以通过形态学分为不同的类型。局部型是最常见的 ONL 类型，多级 ONL 多发生于 OPLL 患者。 C4,5和C5,6是ONL最常发生的水平。证据等级：4

Study Design. Retrospective clinical data analysis. Objective. This study was conducted to investigate the incidence, related factors, and radiography findings of ossification of the nuchal ligament (ONL) in patient with cervical spondylosis, which could serve as a basis for further studies of the relationships between ONL and cervical spondylosis. Summary of Background Data. Injury to nuchal ligament, which might cause ONL, may aggravate cervical spine instability, leading to cervical spondylosis. Thus, it is important to understand the characteristics of ONL in patients who are diagnosed with cervical spondylosis. Methods. Medical records of 372 patients with cervical spondylosis were reviewed. Data analysis included patients' sex, age, location and classification of ONL, and ossification of the posterior longitudinal ligament (OPLL). Radiological features were evaluated by lateral plain radiography and computed tomography for 2-dimensional sagittal plane reconstruction. Results. Of the 372 patients with cervical spondylosis, 49.7% had a diagnosis of ONL; the incidence of ONL was higher in males than in females (P = 0.001) and in elderly patients than in young patients (P = 0.005). The varying pictures of ONL on the plain radiography were classified into 5 types: local, continuous, segmental, mixed, and unclassified, and the distribution was 49.7%, 33.0%, 3.2%, 8.6%, and 5.4%, respectively. ONL occurred mostly at the level of C4,5 (75.7%) and C5,6 (81.1%). The incidence of ONL was higher in patients with OPLL than others (P < 0.001), and the incidence of multilevel ONL was higher in patients with OPLL than in patients with ONL only (P = 0.038). Conclusion. The incidence of ONL is 49.7% in patients with cervical spondylosis. Sex, age, and OPLL are related factors of ONL. ONL can be classified into different types through morphology. Local type is the most common type of ONL, and multilevel ONL occurs mostly in patients with OPLL. C4,5 and C5,6 are the levels where ONL occurs mostly. Level of Evidence: 4

Analysis of Radiography Findings of Ossification of Nuchal Ligament of Cervical Spine in Patients With Cervical Spondylosis

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