Ocular infection of mice with an avirulent recombinant HSV-1 expressing IL-4 and an attenuated HSV-1 strain generates virulent recombinants in vivo.
Ocular infection of mice with an avirulent recombinant HSV-1 expressing IL-4 and an attenuated HSV-1 strain generates virulent recombinants in vivo.
复制标题
用表达 IL-4 的无毒力重组 HSV-1 和减毒 HSV-1 株对小鼠进行眼部感染,可在体内产生剧毒重组体。
作者:
Mott,KevinR;Wechsler,StevenL;Ghiasi,Homayon