In vivo estimation of left ventricular wall volume in volume-overloaded canine hearts.
In vivo estimation of left ventricular wall volume in volume-overloaded canine hearts.
复制标题
体积超载的犬心脏左心室壁体积的体内估计。
DOI：
10.1152/ajpheart.1988.255.6.h1399
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Rankin,JS
中科院分区：
文献类型：
--
作者：
Feneley,MP;Gaynor,JW;Maier,GW;GallJr,SA;Kisslo,JA;Rankin,JS
一些几何算法已被应用于估计左心室壁容积（Vwall）从二维超声心动图，但尚未在偏心性肥厚的心脏得到验证。这些算法可以拟合为以下通式：Vwall = k.Ao.Lo = k.Ai.Li，其中Ao和Ai是外（心外膜）和内（心内膜）短轴面积，Lo和Li是相应的长轴长度，并且k是常数。Lo和Li相等的简化假设产生Vwall = k.Awall.Lo，其中Awall = Ao-Ai。在20只未镇静的狗（10-30 kg）中，包括10只持续1-18周的主动脉瓣返流，实际Vwall（死后测定）和Awall.Lo之间的关系与同一性线无显著差异（Vwall = 1.01 Awall.Lo + 0.5 ml，r = 0.98，SEE = 3.5 ml），表明k与1无显著差异。在31-105 ml范围内，预测和实际Vwall之间无显著差异，观察者间变异性为4.1%。简单的面积长度产品，Awall.Lo，准确地预测Vwall的正常和容量超负荷肥厚犬左心室，因此适合于连续观察肥大适应容量超负荷。
Several geometric algorithms have been applied to estimate left ventricular wall volume (Vwall) from two-dimensional echocardiograms but have not been validated in eccentrically hypertrophied hearts. These algorithms can be fitted to the general formula: Vwall = k.Ao.Lo = k.Ai.Li, where Ao and Ai are the outer (epicardial) and inner (endocardial) short-axis areas, Lo and Li are the corresponding long-axis lengths, and k is a constant. The simplifying assumption that Lo and Li are equal yields Vwall = k.Awall.Lo, where Awall = Ao - Ai. In 20 unsedated dogs (10–30 kg), including 10 with aortic regurgitation of 1–18 wk duration, the relationship between actual Vwall (determined postmortem) and Awall.Lo was not significantly different from the line of identity (Vwall = 1.01 Awall.Lo + 0.5 ml, r = 0.98, SEE = 3.5 ml), indicating k was not significantly different from 1. There was no significant difference between predicted and actual Vwall over a range of 31–105 ml, and interobserver variability was 4.1%. The simple area-length product, Awall.Lo, accurately predicts Vwall of both normal and volume-overloaded hypertrophied canine left ventricles and is thus suitable for serial observations of hypertrophic adaptation to volume overload.