Clinical presentation of parvovirus B19 infection in children with aplastic crisis
Clinical presentation of parvovirus B19 infection in children with aplastic crisis
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DOI：
10.1097/01.inf.0000101783.73240.4a
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发表时间：
2003-12-01
影响因子：
3.6
通讯作者：
Grossi, M
中科院分区：
文献类型：
--
作者：
Kellermayer, R;Faden, H;Grossi, M
The records of 22 children with parvovirus B19-induced aplastic crisis were reviewed. The group consisted of 16 children with sickle cell hemoglobinopathies and 6 with hereditary spherocytosis. Children presented to the hospital 0.5 to 8 days (mean, 2.4 days) after the onset of symptoms. The children with sickle-cell disease presented earlier (mean, 1.4 days) than did children with hereditary spherocytosis mean, 5 days; P = 0.02. Fever was the most common symptom, occurring in 73% of children. Rash did not occur in either group. Reticulocyte counts began to rise 1 week after onset of illness associated with a rise in parvovirus B19-specific IgG antibody. These data suggest that parvovirus B19 infection in children with sickle-cell hemoglobinopathies and heredity spherocytosis differs from infection in normal children.
