Time course of recovery from nerve injury in skeletal muscle: Energy state and local circulation
Time course of recovery from nerve injury in skeletal muscle: Energy state and local circulation
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DOI：
10.1152/jappl.1997.82.3.732
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发表时间：
1997-03-01
影响因子：
3.3
通讯作者：
Koga, K
中科院分区：
文献类型：
--
作者：
Hayashi, Y;Ikata, T;Koga, K
This study examined the time course of recovery from nerve injury on energy state assessed by phosphorus-31 magnetic resonance spectroscopy and local circulation dynamics by fluorine-19 magnetic resonance spectroscopy in skeletal muscles of rats. The hindlimb muscles that had undergone unilateral sciatic nerve compression for 2 wk (CN) were compared with sham-operated (SO) muscles and with muscles that had the compression removed after 2 wk and were allowed to recover for 4 wk (R4) or for 6 wk (R6). The energy state and local circulation dynamics of CN muscles were less than those of SO muscles (P < 0.01). The energy state of R4 muscles remained at levels similar to CN muscles, whereas the local circulation dynamics improved but not back to SO values. In R6 muscles, both parameters returned to SO values. These results showed that the recovery processes of circulation precede those of energy state in skeletal muscles.
