Neurodevelopmental outcome in preschool survivors of complex congenital heart disease: implications for clinical practice.
Neurodevelopmental outcome in preschool survivors of complex congenital heart disease: implications for clinical practice.
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DOI：
10.1016/j.pedhc.2006.03.008
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发表时间：
2007-01-01
期刊：
影响因子：
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通讯作者：
Tweddell, James S
中科院分区：
文献类型：
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作者：
Brosig, Cheryl L;Mussatto, Kathleen A;Tweddell, James S
简介：本研究的目的是描述现代外科时代学龄前左心发育不全综合征（HLHS）和大动脉转位（TGA）幸存者的神经发育结局。方法：采用横断面设计对中西部一家儿童医院的26名儿童（13名HLHS， 13名TGA）进行评估，年龄为3.5至6岁。测量方法包括麦卡锡儿童能力量表、伍德考克·约翰逊成就测验、视觉运动综合发展测验、接受性单字词汇测验、表达性单字词汇测验和儿童行为检查表。结果：虽然两组的智商得分均在平均范围内（TGA=110.5 vs. HLHS=97），但两组之间的差异具有临床意义（效应值= 0.79）。与TGA组相比，HLHS组在视觉运动技能、表达性语言、注意力和外化行为方面表现出更多的问题。讨论：结果表明，即使在现代外科时代，对这些患者进行定期发育筛查也是至关重要的。儿科护士从业者在教育家长关于这些儿童的潜在发育风险方面发挥着重要作用。
INTRODUCTION: The purpose of this study was to describe the neurodevelopmental outcome of preschool survivors of Hypoplastic Left Heart Syndrome (HLHS) and Transposition of the Great Arteries (TGA) in the modern surgical era.METHODS: A cross-sectional design was used to evaluate 26 children (13 HLHS, 13 TGA), ages 3.5 to 6 years, at a Midwestern children's hospital. Measures included McCarthy Scales of Children's Abilities, Woodcock Johnson III Tests of Achievement, Developmental Test of Visual-Motor Integration, Receptive One-Word Vocabulary Test, Expressive One-Word Vocabulary Test, and Child Behavior Checklist.RESULTS: Although intelligence quotient scores fell within the average range for both groups (TGA=110.5 vs. HLHS=97), the difference between groups was clinically meaningful (effect size= .79). The HLHS group showed more problems than did the TGA group with visual-motor skills, expressive language, attention, and externalizing behavior.DISCUSSION: Results suggest that even in the modern surgical era, regular developmental screening for these patients is critical. Pediatric nurse practitioners play an important role in educating parents about the potential developmental risks to these children.