Antiserum to lens antigens immunostains Müller glia cells in the neural retina.
Antiserum to lens antigens immunostains Müller glia cells in the neural retina.
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晶状体抗原的抗血清对神经视网膜中的穆勒神经胶质细胞进行免疫染色。
DOI：
10.1073/pnas.82.16.5570
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发表时间：
1985
影响因子：
11.1
通讯作者：
L. Degenstein
中科院分区：
文献类型：
--
作者：
A. Moscona;L. Fox;J. Smith;L. Degenstein
富含α-晶状体蛋白的透镜组分的抗血清选择性免疫染色几种脊椎动物神经视网膜中的Müller神经胶质细胞。此外，在胚胎视网膜（鸡）中，这种抗血清与Müller细胞反应，并在发育的早期阶段与其明显的前体反应。因此，针对透镜产品的抗体可检测Müller神经胶质细胞标志物，该标志物在其个体发育的极早期开始表达，并可用于研究该细胞类型的分化、功能和病理学。
Antiserum to a lens fraction enriched for alpha-crystallin selectively immunostains Müller glia cells in the neural retina of several vertebrate species. Also, in embryonic retina (chicken), this antiserum reacts with Müller cells and, at early stages of development, with their apparent precursors. Thus, antibodies to a lens product(s) detect a Müller glia cell marker that begins to be expressed very early in their ontogeny and can be useful in studies on differentiation, function, and pathologies of this cell type.