ON THE THEORY OF THE INDICATOR-DILUTION METHOD FOR MEASUREMENT OF BLOOD FLOW AND VOLUME
ON THE THEORY OF THE INDICATOR-DILUTION METHOD FOR MEASUREMENT OF BLOOD FLOW AND VOLUME
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DOI：
10.1152/jappl.1954.6.12.731
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发表时间：
1954-01-01
影响因子：
3.3
通讯作者：
ZIERLER, KL
中科院分区：
文献类型：
--
作者：
MEIER, P;ZIERLER, KL
如图。 I. 血管床示意图，包括注射部位 P、P' 和采样部位 Q、Q'。指示剂稀释技术提供合理的平均 CI 测量的情况。循环时间。特别是，瞬时注射和恒定注射技术将显示出本质上相同的优点和缺陷。由于后一种方法避免了对前一种方法的一些批评，因此它们的等价性可以被视为对瞬时注射技术的额外支持。血管床的复杂性在很大程度上掩盖了这些问题。为了阐明斯图尔特-汉密尔顿方法的基本原理，我们首先考虑一个相对简单的模型，其中不会出现某些复杂性。第 3 节考虑了这些并发症的影响。
FIG. I. Schema of vascular bed with injection sites P, P’and sampling sites Q, Q’. circumstances under which the indicator-dilution technics provide reasonable measures of mean ci. rculation time. In particular, the instantaneous injection and constant injection technics will be shown to share essentially the same advantages and defects. As the latter method has escaped some of the criticism applied to the former, their equivalence may be regarded as additional support for the instantaneous injection technic.The issues are obscured to a considerable extent by the complex nature of a vascular bed. In order to make clear the rationale of the Stewart-Hamilton methods we will consider first a relatively simple model in which certain complications do not arise. The effects of these complications are considered in SECTION 3.