Early Childhood Adversity, Toxic Stress, and the Role of the Pediatrician: Translating Developmental Science Into Lifelong Health
Early Childhood Adversity, Toxic Stress, and the Role of the Pediatrician: Translating Developmental Science Into Lifelong Health
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DOI：
10.1542/peds.2011-2662
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发表时间：
2012-01-01
期刊：
影响因子：
8
通讯作者：
Wood, David L.
中科院分区：
文献类型：
--
作者：
Garner, Andrew S.;Shonkoff, Jack P.;Wood, David L.
生物、行为和社会科学的广泛进展正在扩大我们对早期环境影响（生态学）和遗传倾向（生物学程序）如何影响学习能力、适应行为、终身身心健康和成年生产力的理解。美国儿科学会（AAP）的一份支持性技术报告提出了一个综合的生态发育框架，以帮助将这些发展科学的巨大进步转化为改善整个生命周期的健康状况。儿科医生现在掌握了有关毒性应激对大脑发育不利影响的新信息，以及对许多成人疾病的早期生命起源有了更深入的了解。作为儿童健康和发展方面值得信赖的权威，儿科提供者现在必须在早期发现发展问题的同时，更加注重那些减少对大脑健康生长的外部威胁的干预措施和社区投资。为此，美国儿科学会支持在整个儿科社区中发挥领导作用——调动基础和临床研究人员的科学专业知识，儿科医疗之家以家庭为中心的护理，以及美国儿科学会及其各州分会的公共影响力——促进幼儿政策和服务的根本变化。美国儿科学会致力于利用科学为制定创新战略提供信息，以减少幼儿有毒压力的诱因，并减轻其对整个生命周期的发育和健康过程的负面影响。儿科2012;129: e224-e231
Advances in a wide range of biological, behavioral, and social sciences are expanding our understanding of how early environmental influences (the ecology) and genetic predispositions (the biologic program) affect learning capacities, adaptive behaviors, lifelong physical and mental health, and adult productivity. A supporting technical report from the American Academy of Pediatrics (AAP) presents an integrated ecobiodevelopmental framework to assist in translating these dramatic advances in developmental science into improved health across the life span. Pediatricians are now armed with new information about the adverse effects of toxic stress on brain development, as well as a deeper understanding of the early life origins of many adult diseases. As trusted authorities in child health and development, pediatric providers must now complement the early identification of developmental concerns with a greater focus on those interventions and community investments that reduce external threats to healthy brain growth. To this end, AAP endorses a developing leadership role for the entire pediatric community-one that mobilizes the scientific expertise of both basic and clinical researchers, the family-centered care of the pediatric medical home, and the public influence of AAP and its state chapters-to catalyze fundamental change in early childhood policy and services. AAP is committed to leveraging science to inform the development of innovative strategies to reduce the precipitants of toxic stress in young children and to mitigate their negative effects on the course of development and health across the life span. Pediatrics 2012;129:e224-e231