THE LOCALIZING VALUE OF DEPTH ELECTROENCEPHALOGRAPHY IN 32 PATIENTS WITH REFRACTORY EPILEPSY
THE LOCALIZING VALUE OF DEPTH ELECTROENCEPHALOGRAPHY IN 32 PATIENTS WITH REFRACTORY EPILEPSY
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DOI：
10.1002/ana.410120306
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发表时间：
1982-01-01
影响因子：
11.2
通讯作者：
MATTSON, RH
中科院分区：
文献类型：
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作者：
SPENCER, SS;SPENCER, DD;MATTSON, RH
对 32 名患者进行了临床癫痫表现、体格检查、放射学研究、神经心理学测试以及头皮和深度脑电图 (EEG) 研究来定位癫痫病灶，其中 23 名患者接受了手术并进行了一年以上的随访。在 16 名头皮脑电图未定位的患者中，深度脑电图检测到 3 名患者出现一致的局灶性癫痫发作。在 15 名局部头皮脑电图患者中，深度脑电图显示 3 名患者有多个病灶，4 名患者的头皮脑电图病灶定位不准确。因此，31 名患者中，有 10 名患者的头皮脑电图定位不准确。当深度脑电图显示一致的局灶性癫痫发作并使用该定位来确定手术切除部位时，13 名患者中有 12 名获得了良好至极好的结果。当深度脑电图显示额外的癫痫发作灶时，所有患者的手术结果都可以或较差。没有其他定位标准能够如此准确地预测深度脑电图结果或手术成功。此外，一些标准，包括神经心理学测试和放射学异常，有时会错误地定位。因此，在目前可用的定位标准中，深度脑电图似乎是最准确的。
Clinical seizure manifestations, physical examination, radiological studies, neuropsychological tests, and scalp and depth electroencephalographic (EEG) studies were done to localize seizure foci in 32 patients, 23 of whom have undergone surgery with more than one year of follow‐up. Of 16 patients with unlocalized scalp EEGs, depth EEG detected a consistent focal seizure onset in 3. Of 15 patients with localized scalp EEGs, depth EEG revealed multiple foci in 3 and inaccurate localization of the focus by scalp EEG in 4. Therefore, localization by scalp EEG was inaccurate in 10 of 31 patients. When depth EEG revealed a consistent focal seizure onset and this localization was used to determine the surgical resection site, good to excellent results were obtained in 12 of 13 patients. When depth EEG revealed additional foci of seizure origin, surgical results were fair or poor in all patients. No other localizing criteria predicted depth EEG results or surgical success with such accuracy. Furthermore, some criteria, including neuropsychological tests and radiological abnormalities, were falsely localizing at times. Therefore, of the presently available localizing criteria, depth EEG appears to be the most accurate.