Epitope imprinted polyethersulfone beads by self-assembly for target protein capture from the plasma proteome.

Epitope imprinted polyethersulfone beads by self-assembly for target protein capture from the plasma proteome.
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DOI:
10.1039/c4cc03428g
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发表时间:
2014-07
影响因子:
4.9
通讯作者:
Kaiguang Yang;Jianxi Liu;Senwu Li;Qinran Li;Qi Wu;Yuan Zhou;Qun Zhao;Nan Deng;Zhen Liang;Lihua Zhang;Yukui Zhang
Kaiguang Yang;Jianxi Liu;Senwu Li;Qinran Li;Qi Wu;Yuan Zhou;Qun Zhao;Nan Deng;Zhen Liang;Lihua Zhang;Yukui Zhang
中科院分区:
化学2区
文献类型:
--
作者:
Kaiguang Yang;Jianxi Liu;Senwu Li;Qinran Li;Qi Wu;Yuan Zhou;Qun Zhao;Nan Deng;Zhen Liang;Lihua Zhang;Yukui Zhang

文献摘要

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聚合物自组装作为一种表位印迹技术被开发出来,其过程简单,识别位点密度高。作为模型,利用该技术成功制备了转铁蛋白表位印迹聚醚砜(PES)微球。印迹微球对转铁蛋白表位和转铁蛋白具有良好的选择性,即使在实际样品中也是如此。
Polymer self-assembly was developed as an epitope imprinting strategy involving facile processes and high recognition site density. As a model, transferrin epitope imprinted polyethersulfone (PES) beads were successfully fabricated using this technique. The imprinted beads demonstrated excellent selectivity toward the transferrin epitope and transferrin even in the real sample.