From affected to infected? Orphanhood and HIV risk among female adolescents in urban Zimbabwe
From affected to infected? Orphanhood and HIV risk among female adolescents in urban Zimbabwe
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DOI：
10.1097/qad.0b013e3282f4cac7
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发表时间：
2008-03-30
期刊：
影响因子：
3.8
通讯作者：
Glynn, Judith R.
中科院分区：
文献类型：
--
作者：
Birdthistle, Isolde J.;Floyd, Sian;Glynn, Judith R.
背景资料：尽管有15万艾滋病孤儿的儿童，并担心性的脆弱性，鲜为人知的是，在2004年的一项横断面调查中确定了1283 15至19岁的女孩在一个高密度的郊区哈拉雷的随机样本之间的联系。共有863人同意接受采访，839人提供了艾滋病毒和单纯疱疹病毒2型（HSV-2）检测样本。性健康的结果，性行为和婚姻的类型和时机进行了评估birthhood.Results：一半的参与者是单或双孤儿。孤儿中HIV和/或HSV-2的患病率高于非孤儿[17%对12%;年龄校正比值比（aOR）=1.5; 95%置信区间（CI）1.0-2.3]。只有在743名从未结婚的参与者中，与孤儿身份的关联才显着。与非孤儿同龄人相比，（定义为HSV 2阳性，HIV阳性或曾经怀孕）（aOR = 3.6; 95% CI，1.7-7.8），双孤儿（aOR = 2.4; 95%CI，1.2-4.9），和女孩谁失去了他们的父亲在12岁之前（aOR = 2.1; 95%CI，0.9-4.8），但不是更晚（aOR = 0.8; 95%CI，0.3-2.2）。产妇和双孤儿最有可能开始性行为早，有多个合作伙伴。产妇孤儿在第一次性行为中使用避孕套的可能性最小，并且有固定的性伴侣。强迫性行为的经验是高的，在所有groups.Conclusions：在津巴布韦城市，女性青少年孤儿艾滋病毒和HSV-2感染的风险增加。感染率因生育类型和年龄以及婚姻状况而异，并与高风险性行为有关。(C)2008年威科健康|利平科特威廉姆斯&威尔金斯。
Background: Despite the 15 million children orphaned by AIDS, and fears of sexual vulnerability, little is known about the link between orphanhood and HIV risk.Methods: A random sample of 1283 15 to 19-year-old girls in a high-density suburb of Harare was identified in a cross-sectional survey in 2004. A total of 863 agreed to be interviewed and 839 provided a specimen for HIV and herpes simplex virus type-2 (HSV-2) testing. Sexual health outcomes, sexual behaviours and marriage were assessed by type and timing of orphanhood.Results: Half of the participants were single or double orphans. Prevalence of HIV and/or HSV-2 was higher among orphans than non-orphans [17 versus 12%; age-adjusted odds ratio (aOR)=1.5; 95% confidence interval (CI) 1.0-2.3]. Associations with orphan status were only significant among the 743 never-married participants. In comparison with non-orphaned peers, increased sexual risk (defined as HSV2-positive, HIV-positive or ever pregnant) was seen among maternal orphans (aOR = 3.6; 95% CI, 1.7-7.8), double orphans (aOR = 2.4; 95% CI, 1.2-4.9), and girls who lost their father before age 12 (aOR = 2.1; 95% CI, 0.9-4.8) but not later (aOR = 0.8; 95% CI, 0.3-2.2). Maternal and double orphans were most likely to initiate sex early and to have had multiple partners. Maternal orphans were least likely to have used a condom at first sex, and to have a regular sexual partner. Experience of forced sex was high in all groups.Conclusions: In urban Zimbabwe, female adolescent orphans are at increased risk of HIV and HSV-2 infection. Infection rates vary by type and age of orphanhood, and marital status, and are associated with high-risk sexual behaviours. (C) 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins.