Update on Human Immunodeficiency Virus (HIV)-2 Infection
Update on Human Immunodeficiency Virus (HIV)-2 Infection
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DOI：
10.1093/cid/ciq248
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发表时间：
2011-03-15
影响因子：
11.8
通讯作者：
Gandhi, Rajesh T.
中科院分区：
文献类型：
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作者：
Campbell-Yesufu, Omobolaji T.;Gandhi, Rajesh T.
人类免疫缺陷病毒2型（HIV-2）的感染主要发生在西非，但越来越多的病例在欧洲，印度和美国得到了认可。在这个全球整合的时代，临床医生必须意识到何时考虑诊断HIV-2感染以及如何测试该病毒。尽管关于何时应开始治疗并选择哪些方案存在争议，但最近的试验提供了有关HIV-2感染治疗方案的重要信息。在这篇综述中，我们介绍了有关对HIV-2感染的理解，并突出诊断性和治疗性挑战的最新临床进展信息。
Infection with human immunodeficiency virus type 2 (HIV-2) occurs mainly in West Africa, but an increasing number of cases have been recognized in Europe, India, and the United States. In this era of global integration, clinicians must be aware of when to consider the diagnosis of HIV-2 infection and how to test for this virus. Although there is debate regarding when therapy should be initiated and which regimen should be chosen, recent trials have provided important information on treatment options for HIV-2 infection. In this review, we present information on recent clinical advances in our understanding of HIV-2 infection and highlight remaining diagnostic and therapeutic challenges.