Computation of residence time in the simulation of pulsatile ventricular assist devices
Computation of residence time in the simulation of pulsatile ventricular assist devices
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DOI：
10.1007/s00466-013-0931-y
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发表时间：
2014-10-01
影响因子：
4.1
通讯作者：
Bazilevs, Y.
中科院分区：
文献类型：
--
作者：
Long, C. C.;Esmaily-Moghadam, M.;Bazilevs, Y.
提出了一种用于运动域流体力学和流固耦合（FSI）计算的基于连续体的粒子停留时间模型，对其进行了分析，并将其应用于成人搏动心室辅助装置（PVAD）的仿真。停留时间是临床对血泵感兴趣的一个量，因为它与血栓形成风险相关。所提出的技术可以很容易地在任何流或FSI求解器中实现。在PVADs的情况下，该模型的结果可用于评估泵通过其内部移动血液的效率。提出了粒子停留时间的三种标量度量方法。这些标量可用于PVAD设计与降低血栓风险的目标。
A continuum-based model of particle residence time for moving-domain fluid mechanics and fluid-structure interaction (FSI) computations is proposed, analyzed, and applied to the simulation of an adult pulsatile ventricular assist device (PVAD). Residence time is a quantity of clinical interest for blood pumps because it correlates with thrombotic risk. The proposed technique may be easily implemented in any flow or FSI solver. In the context of PVADs the results of the model may be used to assess how efficiently the pump moves the blood through its interior. Three scalar measures of particle residence time are also proposed. These scalar quantities may be used in the PVAD design with the goal of reducing thrombotic risk.