Palladium-catalyzed double C-H functionalization of 2-aryl-1,3-dicarbonyl compounds: a facile access to alkenylated benzopyrans
Palladium-catalyzed double C-H functionalization of 2-aryl-1,3-dicarbonyl compounds: a facile access to alkenylated benzopyrans
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DOI：
10.1016/j.tetlet.2016.04.089
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发表时间：
2016-06-08
影响因子：
1.8
通讯作者：
Bollikolla, Had Babu
中科院分区：
文献类型：
--
作者：
Choppakatla, Subrahmanyam;Dachepally, Aravind Kumar;Bollikolla, Had Babu
本研究报道了钯催化氧化环/亲核取代序列的发展，提供了一个由2-芳基-1,3-二羰基化合物和烯丙基乙酸酯组成的烯基化苯并吡喃化合物库。该工艺与具有良好官能团耐受性的广泛底物兼容，以中等至良好的产量产生所需的杂环。(C) 2016 Elsevier Ltd.版权所有。
The present study reports the development of a palladium-catalyzed oxidative annulation/nucleophilic substitution sequence affording a library of alkenylated benzopyrans using 2-aryl-1,3-dicarbonyl compounds and allylic acetate. The process is compatible to a wide range of substrates with good functional group tolerance producing the desired heterocycles in moderate to good yields. (C) 2016 Elsevier Ltd. All rights reserved.