Spinal lipomas: clinical spectrum, embryology, and treatment.
Spinal lipomas: clinical spectrum, embryology, and treatment.
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DOI：
10.3171/foc-07/08/e10
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发表时间：
2007-12
影响因子：
4.1
通讯作者：
Michael A. Finn;M. Walker
中科院分区：
文献类型：
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作者：
Michael A. Finn;M. Walker
脊柱脂肪瘤，尤其是脊髓圆锥和终丝的脂肪瘤，是隐匿性脊柱闭合不全的最常见形式，在解剖、临床表现和治疗方案方面代表了广泛的疾病范围。然而，这些损害由相似的胚胎学和出现症状的病理机制结合在一起。最近，这些病变的治疗引起了很大争议，一些医生主张对所有患者进行手术治疗，而不考虑症状，另一些医生则建议推迟手术，直到症状出现。作者讨论了腰骶椎脂肪瘤，特别关注其起源、解剖和病理特征的理论，以及治疗选择，包括对当前争议的回顾。
Spinal lipomas, particularly lipomas of the conus medullaris and terminal filum, are the most common form of occult spinal dysraphism and represent a wide spectrum of disease with regard to anatomy, clinical presentation, and treatment options. These lesions, however, are united by a similar embryology and pathological mechanism by which symptoms arise. Recently, the treatment of these lesions has generated much controversy, with some physicians advocating surgical treatment for all patients regardless of symptoms and others proposing that surgery be withheld until symptoms develop. The authors discuss lumbosacral spinal lipomas, with particular attention to the theories of their origin, anatomical and pathological features, and treatment options, including a review of current controversies.