A Causal Role for Primary Motor Cortex in Perception of Observed Actions.
A Causal Role for Primary Motor Cortex in Perception of Observed Actions.
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DOI：
10.1162/jocn_a_01015
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发表时间：
2016-12
影响因子：
3.2
通讯作者：
Kilner JM
中科院分区：
文献类型：
--
作者：
Palmer CE;Bunday KL;Davare M;Kilner JM
有人提出，运动系统的活动，在行动观察可以调制所观察到的行动的运动学。在动作观察期间的该活动的一个目的可以是基于他们的运动运动学来预测另一个人的动作的视觉后果。在这里，我们测试的假设，初级运动皮层（M1）可能有一个因果关系的作用，推断信息是存在于所观察到的动作的运动学。健康受试者在左侧M1上施加连续θ爆发刺激（cTBS）之前和之后完成了动作感知任务。使用神经生理学标记物来量化cTBS后M1破坏的程度，并先验地对我们的样品进行分层以提供内部对照。我们发现，M1的中断导致个人的敏感性降低，以解释观察到的动作的运动学;运动兴奋性的抑制幅度预测了这种敏感性的变化。
It has been proposed that motor system activity during action observation may be modulated by the kinematics of observed actions. One purpose of this activity during action observation may be to predict the visual consequence of another person’s action based on their movement kinematics. Here, we tested the hypothesis that the primary motor cortex (M1) may have a causal role in inferring information that is present in the kinematics of observed actions. Healthy participants completed an action perception task before and after applying continuous theta burst stimulation (cTBS) over left M1. A neurophysiological marker was used to quantify the extent of M1 disruption following cTBS and stratify our sample a priori to provide an internal control. We found that a disruption to M1 caused a reduction in an individual’s sensitivity to interpret the kinematics of observed actions; the magnitude of suppression of motor excitability predicted this change in sensitivity.