Roux-en-Y choledochojejunostomy using novel magnetic compressive anastomats in canine model of obstructive jaundice

Roux-en-Y choledochojejunostomy using novel magnetic compressive anastomats in canine model of obstructive jaundice
复制标题

在梗阻性黄疸犬模型中使用新型磁性压缩吻合器进行 Roux-en-Y 胆总管空肠吻合术

DOI:
10.1016/s1499-3872(11)60129-x
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发表时间:
2012-02-01
影响因子:
3.3
通讯作者:
Lv, Yi
Lv, Yi
中科院分区:
医学3区
文献类型:
--
作者:
Fan, Chao;Yan, Xiao-Peng;Lv, Yi

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背景技术背景:传统的胆肠Roux-en-Y吻合术技术复杂,术后并发症发生率高。方法:将16只犬随机分为两组,每组8只,结扎胆总管7 d后,取胆总管空肠,用自制的磁性压迫器行胆总管空肠吻合术。研究组采用吻合口,对照组采用传统的手工缝合方法进行标准Roux-en-Y胆肠吻合。比较两组患者术后1个月和3个月的手术时间、并发症发生率、大体外观和吻合口病理差异。两组均未发生吻合口狭窄,但对照组胆肠吻合口狭窄率明显高于对照组。对照组有1例胆漏,而研究组无胆漏发生。一个更光滑的表面,一个改进的层贴壁,和较低的局部炎症反应被确定在吻合的studygroup.CONCLUSION:新型磁压缩支架的结构简单,他们是省时,安全和有效的执行Roux-en-Y胆肠吻合术程序在犬梗阻性黄疸模型。(肝胆胰疾病国际2012;11:81-88)
BACKGROUND: The traditional hand-sewn Roux-en-Y choledochojejunostomy is technically complicated, and the incidence of postoperative complications has remained high. A set of novel magnetic compressive anastomats was introduced to facilitate choledochojejunostomy and improve the prognosis of patients.METHODS : After ligating the common bile duct for 7 days, 16 dogs were randomly divided into two groups (n=8 per group). Anastomats were used in the study group, and the traditional hand-sewn method was used in the control group for standard Roux-en-Y choledochojejunostomy. We compared the operation time, incidence of complications, gross appearance, and pathological disparity in stoma between the two groups in 1-month and 3-month follow-tip examinations.RESULTS: The time spent on constructing the anastomosis for the study group was significantly shortened. Although no anastomotic stenosis occurred in the two groups, the narrowing rate of biliary-enteric anastomosis was much higher in the control group. There was one case of bile leakage in the control group, whereas no bile leakage occurred in the study group. A smoother surface, an improved layer apposition, and a lower local inflammatory response were identified in the anastomosis of the study group.CONCLUSION: The structures of the novel magnetic compressive anastomats are simple, and they are time-saving, safe and efficient for performing Roux-en-Y choledochojejunostomy procedures in a canine model of obstructive jaundice. (Hepatobiliary Pancreat Dis Int 2012;11:81-88)