Added value of three-way methods for the analysis of mortality trends illustrated with worldwide female cancer mortality (1968-1985)

Added value of three-way methods for the analysis of mortality trends illustrated with worldwide female cancer mortality (1968-1985)
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用于分析死亡率趋势的三向方法的附加值以全球女性癌症死亡率(1968-1985)为例

DOI:
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发表时间:
2002
影响因子:
2.3
通讯作者:
J. Coebergh
J. Coebergh
中科院分区:
医学3区
文献类型:
--
作者:
P. Kroonenberg;T. Murakami;J. Coebergh

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死亡率的趋势通常按肿瘤部位或按国家列出,而没有对涵盖所有三个方面(肿瘤部位、国家、趋势)的完整数据进行总体分析。本文介绍了一种使用三向方法进行全面分析的方法,该方法应用于1968 - 1985年43个国家17个肿瘤部位的女性死亡率数据集。多变量技术,如biplots和三模式主成分分析的整体三因素方差分析框架内使用。我们证实了已知的模式,即膀胱癌、肠癌、胰腺癌、直肠癌、乳腺癌、卵巢癌、皮肤癌和白血病导致的妇女死亡率较高,而西欧和北方、美国、澳大利亚和新西兰的肝癌死亡率相对较低。此外,中欧和南欧、香港、新加坡和日本以及部分但并非全部拉丁美洲国家的情况正好相反。在不列颠群岛,肺癌、口腔癌、喉癌和食道癌的相对死亡率较高,但在其他欧洲国家则低得多。在中欧国家,甲状腺癌、子宫癌、胆囊癌和胃癌的死亡率很高,日本、智利和哥斯达黎加的情况也是如此。南欧国家、北美、澳大利亚和新西兰的比率较低。数据中的特定偏离模式是智利和日本胃癌死亡率下降更快,而美国、苏格兰和丹麦肺癌死亡率上升更快。总之,使用三因素方法,对癌症死亡率数据进行整体分析是可行的。这使得能够同时比较所有国家所有肿瘤部位的相对死亡率趋势,并确定特定国家特定肿瘤部位的特定偏离趋势。
Trends in mortality rates are usually presented per tumour site or per country without an overall analysis of the complete data encompassing all three aspects (tumour sites, countries, trends). This paper presents a methodology for such an overall analysis using three-way methods applied to a data set on female mortality rates for 17 tumour sites of 43 countries for the years 1968-1985. Multivariate techniques like biplots and three-mode principal component analysis within an overall three-way analysis-of-variance framework were used. We confirmed the known patterns of comparatively high mortality for women due to cancer of the bladder, intestines, pancreas, rectum, breast, ovary, skin and leukaemia and the relatively low mortality rates for liver cancer in Western and Northern Europe, the USA, Australia and New Zealand. Also, the reverse pattern was observed for Middle and Southern Europe, Hong Kong, Singapore, and in Japan, and in some but not all Latin American countries. The relatively mortality due to cancer was high in the lungs, mouth, larynx and oesophagus in the British Isles, but was much less in other European countries. Mortality due to cancer of the thyroid, uterus, gall bladder and stomach was high in Middle European countries, as was the case in Japan, Chile and Costa Rica. Rates were low for Southern European countries, North America, Australia and New Zealand. Specific deviating patterns in the data were the more rapidly decreasing mortality rates for stomach cancer in Chile and Japan and the more rapidly increasing mortality rates for lung cancer in the USA, Scotland and Denmark. In conclusion, using three-way methods, it was feasible to analyse the cancer mortality data in their entirety. This enabled the simultaneous comparison of trends in relative mortality rates between all countries due to all tumour sites, as well as the identification of specific deviating trends for specific tumour sites in specific countries.
国际癌症死亡率的变化:因子和聚类分析。
DOI: 10.1093/ije/16.4.501
发表时间: 1987
影响因子: 7.7
作者:
Groves,FD;Zavala,DE;Correa,P
通讯作者: Correa,P