SEOM clinical guideline for the management of malignant melanoma (2017).

SEOM clinical guideline for the management of malignant melanoma (2017).
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SEOM恶性黑色素瘤管理临床指南(2017年)。

DOI:
10.1007/s12094-017-1768-1
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发表时间:
2018-01
期刊:
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
影响因子:
--
通讯作者:
Algarra SM
Algarra SM
中科院分区:
其他
文献类型:
--
作者:
Berrocal A;Arance A;Castellon VE;de la Cruz L;Espinosa E;Cao MG;Larriba JLG;Márquez-Rodas I;Soria A;Algarra SM

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所有疑似黑色素瘤的患者必须经组织学确诊并切除。前哨淋巴结活检必须在肿瘤直径大于1 mm或小于1 mm且有高危因素的情况下进行。干扰素可以为高危黑色素瘤患者提供辅助治疗,在特定情况下可以加用放射治疗。转移性黑色素瘤的治疗是由突变的BRAF状态指导的。BRAF野生型患者必须接受含有抗PD1的治疗,突变患者必须接受含有BRAF/MEK抑制剂或含有抗PD1的治疗。对于有皮肤科检查和体检的黑色素瘤患者来说,长达10年的随访是合理的。
All melanoma suspected patients must be confirmed histologically and resected. Sentinel node biopsy must be done when tumor is over 1 mm or if less with high-risk factors. Adjuvant therapy with interferon could be offered for patients with high-risk melanoma and in selected cases radiotherapy can be added. Metastatic melanoma treatment is guided by mutational BRAF status. BRAF wild type patients must receive anti-PD1 containing therapy and BRAF mutated patients BRAF/MEK inhibitors or anti-PD1 containing therapy. Up to 10 years follow up is reasonable for melanoma patients with dermatologic examinations and physical exams.
DOI: 10.1056/nejmoa1504030
发表时间: 2015-07-02
期刊: The New England journal of medicine
影响因子: --
作者:
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作者:
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