Effects of TCMC on Transformation of Good Health Status to Suboptimal Health Status: A Nested Case-Control Study.
Effects of TCMC on Transformation of Good Health Status to Suboptimal Health Status: A Nested Case-Control Study.
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TCMC 对良好健康状态向次优健康状态转变的影响：巢式病例对照研究
DOI：
10.1155/2015/259727
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
Zhao X
中科院分区：
文献类型：
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作者：
Wang T;Chen J;Sun X;Xiang L;Zhou L;Li F;Lin C;Jiang P;Wu S;Xiao Y;Cheng J;Luo R;Liu Y;Zhao X
为探讨中医体质对大学生良好健康状态向次优健康状态转化的影响，在中国大学生中进行了巢式病例对照研究。在18个月的平均随访时间内，1273名健康学生中发生了543例（42.7%）SHS。18个月随访时，病例组的SHMS V1.0总分（69.32 ± 5.45）与基线（78.60 ± 4.70）相比有显著（P = 0.000）和显著降低，但对照组无显著变化。条件Logistic回归分析显示，阴虚、气虚体质者发生SHS的危险性分别为2.247倍和2.198倍，阴虚体质者发生SHS的危险性为1.642倍，湿热体质者发生SHS的危险性为1.506倍。而平衡体质是显著的保护因素（OR 0.649; P < 0.05）。总之，这些发现表明，阴虚，气虚，阴虚倾向，湿热倾向似乎引起了SHS的健康状况的变化，而平衡体质似乎抑制了这种变化。因此，调节TCMC的失衡（如阴虚、气虚），可以防止健康状态发展为SHS或导致SHS的消退。
To explore the effects of traditional Chinese medicine constitution (TCMC) on transformation of good health status to suboptimal health status (SHS), we conducted a nested case-control study among college students in China. During the 18-month mean follow-up time, 543 cases of SHS (42.7%) occurred in 1273 healthy students. There was a significant (P = 0.000) and marked reduction in SHMS V1.0 total score in the case group at the 18-month follow-up (69.32 ± 5.45) compared with baseline (78.60 ± 4.70), but there was no significant change in the control group. Conditional logistic regression analysis showed that respondents reporting Yin-deficiency and Qi-deficiency were, respectively, 2.247 and 2.198 times more likely to develop SHS, while tendency to Yin-deficiency and tendency to Damp-heat were, respectively, 1.642 and 1.506 times more likely to develop SHS. However, the Balanced Constitution was a significant protective factor (OR 0.649; P < 0.05). Altogether, these findings demonstrate that Yin-deficiency, Qi-deficiency, tendency to Yin-deficiency, and tendency to Damp-heat appeared to induce a change in health status to SHS, while the Balanced Constitution seemed to restrain this change. We conclude that regulating the unbalanced TCMC (such as Yin-deficiency and Qi-deficiency) may prevent a healthy status developing into SHS or lead to the regression of SHS.