Face encoding and recognition in the human brain
Face encoding and recognition in the human brain
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DOI：
10.1073/pnas.93.2.922
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发表时间：
1996-01-23
影响因子：
11.1
通讯作者：
Grady, CL
中科院分区：
文献类型：
--
作者：
Haxby, JV;Ungerleider, LG;Grady, CL
人类神经系统之间的分离，参与编码和后来的识别新的记忆的面孔被证明是通过测量记忆任务相关的变化，在区域脑血流量与正电子发射断层扫描。与这些记忆功能相关的大脑结构之间几乎没有重叠。右侧海马和邻近皮层的一个区域在记忆编码过程中被激活，但在识别过程中不被激活。新皮层中最引人注目的发现是前额叶参与的一侧化。编码激活了左前额叶皮层，而识别激活了右前额叶皮层。这些结果表明，海马和邻近皮层主要在新的记忆编码时参与记忆功能。此外，面部识别并不是简单地通过编码时执行的操作的重演来介导的，而是涉及解剖学上可分离的操作。
A dissociation between human neural systems that participate in the encoding and later recognition of new memories for faces was demonstrated by measuring memory task-related changes in regional cerebral blood flow with positron emission tomography. There was almost no overlap between the brain structures associated with these memory functions. A region in the right hippocampus and adjacent cortex was activated during memory encoding but not during recognition, The most striking finding in neocortex was the lateralization of prefrontal participation. Encoding activated left prefrontal cortex, whereas recognition activated right prefrontal cortex. These results indicate that the hippocampus and adjacent cortex participate in memory function primarily at the time of new memory encoding. Moreover, face recognition is not mediated simply by recapitulation of operations performed at the time of encoding but, rather, involves anatomically dissociable operations.