INCIDENCE OF OVARIAN METASTASIS IN PATIENTS WITH CANCER OF THE UTERINE CERVIX
INCIDENCE OF OVARIAN METASTASIS IN PATIENTS WITH CANCER OF THE UTERINE CERVIX
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DOI：
10.1016/0090-8258(87)90170-3
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发表时间：
1987-11-01
影响因子：
4.7
通讯作者：
MABUCHI, Y
中科院分区：
文献类型：
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作者：
TABATA, M;ICHINOE, K;MABUCHI, Y
在1970年至1985年期间，706例0期和Ia期宫颈癌患者接受了不切除卵巢的单纯子宫切除术。本文对1977年至1985年间行根治性子宫切除术的326例Ib期至III期浸润性癌患者进行了组织学检查以检测卵巢转移。共674例解剖标本来自日本病理解剖病例年鉴。（日本病理学会，1965 - 1978）。0期和Ia期的随访观察显示卵巢无复发。在浸润性表皮样癌（Ib期至III期）中，尽管21.6%的病例发现盆腔淋巴结转移，但未发现卵巢转移。相反，在宫颈腺癌（纯腺癌和混合性癌）中，48例中有6例（12.5%）出现卵巢转移。77例尸检腺癌中有22例（28.6%）发现卵巢转移，而597例表皮样癌中只有104例（17.4%）发现卵巢转移。这一发现具有统计学意义（P < 0.02）。54例患者中有20例（37.0%）出现卵巢侵犯和转移。该比例明显高于未侵犯卵巢的卵巢转移率（P < 0.001）。
During the period from 1970 to 1985, 706 patients with cervical cancer of stage 0 and Ia were treated by a simple hysterectomy without oophorectomy. In 326 patients with invasive carcinoma in stage Ib to stage III, who were treated by a radical hysterectomy from 1977 to 1985, histological examinations were performed to detect ovarian metastasis. A total of 674 autopsy specimens were obtained from the Annual of the Pathological Autopsy Cases in Japan. (Japanese Pathological Society, 1965 to 1978). Follow-up observations on stage 0 and stage Ia revealed no recurrence in the ovaries. In invasive cases of epidermoid carcinoma (stage Ib to stage III), no ovarian metastases were detected, despite discovery of metastases to the pelvic lymph node in 21.6% of the cases. Conversely, in the cases of cervical adenocarcinoma (pure adenocarcinoma and mixed carcinoma), 6 of 48 cases (12.5%) showed ovarian metastases. Ovarian metastases were found in 22 of 77 (28.6%) autopsy cases of adenocarcinoma, but in only 104 of 597 (17.4%) cases of epidermoid carcinoma. This finding is statistically significant (P < 0.02). Both corpus invasion and metastasis to the ovaries were found in 20 of 54 cases (37.0%). This rate was significantly higher than the rate of ovarian metastasis in cases without corpus invasion (P < 0.001).