Comparison of ossification of demineralized bone, hydroxyapatite, gelfoam, and bone wax in cranial defect repair

Comparison of ossification of demineralized bone, hydroxyapatite, gelfoam, and bone wax in cranial defect repair
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DOI:
10.1097/00001665-199609000-00006
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发表时间:
1996-09-01
影响因子:
0.9
通讯作者:
Zins, J
Zins, J
中科院分区:
医学4区
文献类型:
--
作者:
Papay, FA;Morales, L;Zins, J

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将脱钙同种异体骨移植修复颅骨缺损与其他常用骨填充物进行比较。本研究使用视频数字化X线片分析颅骨缺损骨化,以确定骨缺损钙化及其与术后临床检查和区域对照的关系。术后3个月的临床结果表明,在用脱矿骨和羟基磷灰石填充的钻孔中,骨愈合最好。影像学分析表明,与骨蜡和明胶海绵填充区域相比,脱矿骨填充缺损的钙化。羟基磷灰石颗粒在放射学上是致密的,因此不能准确测量真正的骨愈合。结果表明,与明胶海绵和骨蜡相比,脱钙骨和羟基磷灰石通过骨愈合对限定的颅骨缺损提供了更好的结构支撑。
Demineralized bone allografts in the repair of calvarial defects are compared with other common bone fillers. This study uses a video-digitizing radiographic analysis of calvarial defect ossification to determine calcification of bone defects and its relation to postoperative clinical examination and regional controls. The postoperative clinical results at 3 months demonstrated that bony healing was greatest in bur holes filled with demineralized bone and hydroxyapatite. Radiographic analysis demonstrated calcification of demineralized bone-filled defects compared to bone wax- and Gelfoam-filled regions. Hydroxyapatite granules are radiographically dense, thus not allowing accurate measurement of true bone healing. The results suggest that demineralized bone and hydroxyapatite provide better structural support via bone healing to defined calvarial defects than do Gelfoam and bone wax.