Real-time processing of fast-scan cyclic voltammetry (FSCV) data using a field-programmable gate array (FPGA).
Real-time processing of fast-scan cyclic voltammetry (FSCV) data using a field-programmable gate array (FPGA).
复制标题
使用现场可编程门阵列 (FPGA) 实时处理快速扫描循环伏安法 (FSCV) 数据。
DOI：
10.1109/embc.2014.6944016
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Mohseni,Pedram
中科院分区：
文献类型：
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作者：
Bozorgzadeh,Bardia;Covey,DanielP;Heidenreich,ByronA;Garris,PaulA;Mohseni,Pedram
本文报道了一种数字信号处理（DSP）单元的硬件实现，用于实时处理在碳纤维微电极（CFM）上通过快速扫描循环伏安法（FSCV）获得的数据，这是一种用于高分辨率监测脑神经化学的电化学转导技术。在现场可编程门阵列（FPGA）上实现，DSP单元包括抽取滤波器和嵌入式处理器，以处理过采样的FSCV数据，并真实的时间获得浓度变化的时间曲线，沿着化学特征，以识别目标神经递质。与集成的FSCV传感前端接口，DSP单元可以成功地处理通过在流动池中推注多巴胺以及在麻醉大鼠的背侧纹状体中电诱发的瞬时多巴胺释放获得的FSCV数据。
This paper reports the hardware implementation of a digital signal processing (DSP) unit for real-time processing of data obtained by fast-scan cyclic voltammetry (FSCV) at a carbon-fiber microelectrode (CFM), an electrochemical transduction technique for high-resolution monitoring of brain neurochemistry. Implemented on a field-programmable gate array (FPGA), the DSP unit comprises a decimation filter and an embedded processor to process the oversampled FSCV data and obtain in real time a temporal profile of concentration variation along with a chemical signature to identify the target neurotransmitter. Interfaced with an integrated, FSCV-sensing front-end, the DSP unit can successfully process FSCV data obtained by bolus injection of dopamine in a flow cell as well as electrically evoked, transient dopamine release in the dorsal striatum of an anesthetized rat.