Reversible, Room-Temperature C-C Bond Activation of Benzene by an Isolable Metal Complex
Reversible, Room-Temperature C-C Bond Activation of Benzene by an Isolable Metal Complex
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DOI：
10.1021/jacs.9b05925
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发表时间：
2019-07-17
影响因子：
15
通讯作者：
Aldridge, Simon
中科院分区：
文献类型：
--
作者：
Hicks, Jamie;Vasko, Petra;Aldridge, Simon
The activation of C-C bonds is of fundamental interest in the construction of complex molecules from petrochemical feedstocks. In the case of the archetypal aromatic hydrocarbon benzene, C-C cleavage is thermodynamically disfavored, and is brought about only by transient highly reactive species generated in situ. Here we show that the oxidative addition of the C-C bond in benzene by an isolated metal complex is not only possible, but occurs at room temperature and reversibly at a single aluminium center in [(NON)Al](-) (where NON = 4,5-bis(2,6-diisopropylanilido)-2,7-di-tertbutyl-9,9-dimethylxanthene). Selectivity over C-H bond activation is achieved kinetically and allows for the generation of functionalized acyclic products from benzene.
