ACUTE AND CHRONIC DIARRHEA - HOW TO KEEP LABORATORY TESTING TO A MINIMUM

ACUTE AND CHRONIC DIARRHEA - HOW TO KEEP LABORATORY TESTING TO A MINIMUM
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DOI:
10.1080/00325481.1994.11945891
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发表时间:
1994-09-01
影响因子:
4.2
通讯作者:
MURRAY, JA
MURRAY, JA
中科院分区:
医学4区
文献类型:
--
作者:
TALAL, AH;MURRAY, JA

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诊断腹泻的原因是一项具有挑战性的工作,但如果采用系统的方法进行评估,则可以完成。急性腹泻的病理生理机制(如兰氏贾第鞭虫感染、抗生素使用)与慢性腹泻的病理生理机制(如甲状腺毒症引起的分泌功能障碍、乳糖或果糖不耐受)不同,因此充分的病史和体格检查对于缩小诊断范围至关重要。然后可以利用获得的信息指导实验室调查,并且可以确定腹泻的原因,而无需对患者进行广泛和昂贵的检测。毫无疑问,一些导致腹泻的功能实体有待发现。
Diagnosing a cause of diarrhea is a challenging undertaking but can be accomplished if a systematic approach is used for evaluation. Pathophysiologic mechanisms of acute diarrhea (eg, Giardia Lamblia infection, antibiotic use) are different from those of chronic diarrhea (eg, secretory dysfunction from thyrotoxicosis, lactose or fructose intolerance), so adequate history taking and physical examination are essential in narrowing the diagnosis. Laboratory investigation can then be directed using the information obtained, and the cause of the diarrhea can be established without subjecting the patient to extensive and expensive testing. Undoubtedly, some functional entities that contribute to diarrhea await discovery.