Interdisciplinary Approaches to Food Digestion
Interdisciplinary Approaches to Food Digestion
复制标题
食物消化的跨学科方法
DOI：
10.1007/978-3-030-03901-1_13
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Edwards C
中科院分区：
文献类型：
--
作者：
Edwards C
淀粉是我们饮食中最大的能量来源，也为我们的大脑和红细胞提供了必需的外源性葡萄糖。尽管淀粉类食物在人类营养中发挥着关键作用，但近年来人们开始对其持负面看法，因为从流行病学角度来看，大量食用深加工淀粉与糖尿病和肥胖等一系列负面健康后果有关。膳食淀粉在这些疾病的发展中所起作用的一个关键方面是淀粉的物理结构及其在消化道中消化的速度和程度。结构更容易被消化的淀粉与疾病的发展联系最为密切。用淀粉类食物进行人体干预试验既昂贵又耗时，因此人们开发了一系列体外消化模型作为替代方案。这些模型在模拟人类消化系统的关键方面以及从这些模型中获得的数据的动力学分析方面都取得了重大进展。在本书的这一章，主要模型用于测量淀粉消化率，和他们的用途，进行了审查。此外，这些体外方法与体内方法进行了对比，用于急性干预，以及淀粉类食物消耗的慢性研究结果。
Starch is the largest source of energy in our diet and also provides an essential supply of exogenous glucose to act as fuel for our brains and red blood cells. Despite this key role in human nutrition, in recent years starchy foods have come to be viewed negatively, as consumption of large quantities of heavily processed starch has been epidemiologically linked to a number of negative health outcomes such as diabetes and obesity.A key aspect of the role dietary starch plays in the development of these conditions is the physical structure of the starch and the rate and extent of its digestion in the digestive tract. Starches with structures which are more rapidly digested are those most closely linked with the development of disease. Conducting human intervention trials with starchy foods is expensive and time consuming, so a range of in vitro digestion models have been developed as alternatives. There have been significant advances in these models, both in terms of how closely they mimic key aspects of the human digestive system and in terms of kinetic analysis of data obtained from these models.In this book chapter, the main models used for measuring starch digestibility, and their uses, are reviewed. Additionally, these in vitro approaches are contrasted with in vivo methods for acute interventions, as well as the findings of chronic studies in starchy food consumption.