Bioinformatics Applications Note Data and Text Mining Antigenmap 3d: an Online Antigenic Cartography Resource
Bioinformatics Applications Note Data and Text Mining Antigenmap 3d: an Online Antigenic Cartography Resource
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通讯作者：
J. Barnett;Jialiang Yang;Zhipeng Cai;Tong Zhang;X. Wan
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作者：
J. Barnett;Jialiang Yang;Zhipeng Cai;Tong Zhang;X. Wan
抗原制图是一种通过将抗原投射到二维或三维图中来可视化免疫数据并使误差最小化的有用技术。然而，二维图可能不足以从高维免疫数据中捕捉抗原关系。AntigenMap 3D提供了一种在线、交互式且强大的三维抗原制图构建和可视化资源。AntigenMap 3D可用于识别具有快速抗原变异的病原体（如甲型流感病毒）的抗原变体和疫苗候选株。
Antigenic cartography is a useful technique to visualize and minimize errors in immunological data by projecting antigens to 2D or 3D cartography. However, a 2D cartography may not be sufficient to capture the antigenic relationship from high-dimensional immunological data. AntigenMap 3D presents an online, interactive, and robust 3D antigenic cartography construction and visualization resource. AntigenMap 3D can be applied to identify antigenic variants and vaccine strain candidates for pathogens with rapid antigenic variations, such as influenza A virus.