Trait Loss in Evolution: What Cavefish Have Taught Us about Mechanisms Underlying Eye Regression.
Trait Loss in Evolution: What Cavefish Have Taught Us about Mechanisms Underlying Eye Regression.
复制标题
进化中的特征丧失：穴居鱼告诉我们眼睛退化的机制。
DOI：
10.1093/icb/icad032
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发表时间：
2023
影响因子：
2.6
通讯作者：
Kowalko,Joha
中科院分区：
文献类型：
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作者：
Sifuentes-Romero,Itzel;Aviles,AriM;Carter,JosephL;Chan-Pong,Allen;Clarke,Anik;Crotty,Patrick;Engstrom,David;Meka,Pranav;Perez,Alexandra;Perez,Riley;Phelan,Christine;Sharrard,Taylor;Smirnova,MariaI;Wade,AmandaJ;Kowalko,Joha
特征的减少或完全丧失在整个进化史中是常见的。尽管如此，许多问题仍然存在，为什么和如何性状丧失发生。洞穴动物是一个很好的系统，可以回答这些问题，因为包括眼睛和色素沉着在内的多种特征在洞穴物种种群中一再减少或消失。本文综述了如何盲目的墨西哥洞穴鱼，Astyanax mexicanus，已被用作模型系统研究的发展，遗传和进化机制，洞穴动物的眼睛退化的基础。我们重点关注A中眼球退行如何演变的多个方面。mexicanus，包括有助于眼睛退化的发育和遗传途径，眼睛退化的进化对其他特征的影响，也在A进化。mexicanus，以及导致眼睛退化的进化力量。我们还讨论了什么是已知的重复进化的眼睛退化，无论是在人口ofA。墨西哥的洞穴鱼类和更普遍的洞穴动物。最后，我们提供的观点，如何在未来可以使用洞穴鱼，以进一步阐明机制的特征损失使用的工具和资源，最近成为可用的。
Reduction or complete loss of traits is a common occurrence throughout evolutionary history. In spite of this, numerous questions remain about why and how trait loss has occurred. Cave animals are an excellent system in which these questions can be answered, as multiple traits, including eyes and pigmentation, have been repeatedly reduced or lost across populations of cave species. This review focuses on how the blind Mexican cavefish,Astyanax mexicanus, has been used as a model system for examining the developmental, genetic, and evolutionary mechanisms that underlie eye regression in cave animals. We focus on multiple aspects of how eye regression evolved inA. mexicanus, including the developmental and genetic pathways that contribute to eye regression, the effects of the evolution of eye regression on other traits that have also evolved inA. mexicanus, and the evolutionary forces contributing to eye regression. We also discuss what is known about the repeated evolution of eye regression, both across populations ofA. mexicanuscavefish and across cave animals more generally. Finally, we offer perspectives on how cavefish can be used in the future to further elucidate mechanisms underlying trait loss using tools and resources that have recently become available.