Clinical Features of Infection in Older Adults
Clinical Features of Infection in Older Adults
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DOI：
10.1016/j.cger.2016.02.005
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发表时间：
2016-08-01
影响因子：
3.3
通讯作者：
Norman, Dean C.
中科院分区：
文献类型：
--
作者：
Norman, Dean C.
传染病对老年人的影响远远大于对年轻人的影响，因为感染造成的发病率和死亡率要高得多。造成这种更大影响的原因包括：年龄和慢性疾病导致的生理储备降低、与年龄相关的宿主防御变化、活动能力丧失、多药和药物不良反应的风险更高，以及服用增加感染风险的药物（例如，抗胆碱能药物和其他镇静药物会增加肺炎的风险）。
The impact of infectious diseases on older adults is far greater than on younger adults because of significantly higher morbidity and mortality caused by infection. The reasons for this greater impact include factors such as lower physiologic reserve due to age and chronic disease, age related changes in host defenses, loss of mobility, higher risk for polypharmacy and adverse drug reactions, and being on drugs that increase the risk for infection (e.g., anticholinergic and other sedating medications increase the risk for pneumonia).