Platelets as cellular effectors of inflammation in vascular diseases.

Platelets as cellular effectors of inflammation in vascular diseases.
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DOI:
10.1161/circresaha.113.300512
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发表时间:
2013-05-24
影响因子:
20.1
通讯作者:
Zimmerman GA
Zimmerman GA
中科院分区:
医学1区
文献类型:
--
作者:
Rondina MT;Weyrich AS;Zimmerman GA

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Platelets are chief effector cells in hemostasis. In addition, they are multifaceted inflammatory cells with functions that span the continuum from innate immune responses to adaptive immunity. Activated platelets have key “thromboinflammatory” activities in a variety of vascular disorders and vasculopathies. Recently-identified inflammatory and immune activities provide insights into the biology of these versatile blood cells that are directly relevant to human vascular diseases.