Citrate-based fluorometric sensor for multi-halide sensing.
Citrate-based fluorometric sensor for multi-halide sensing.
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DOI：
10.1016/j.smaim.2022.05.001
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发表时间：
2022
影响因子：
--
通讯作者：
Yang, Jian
中科院分区：
文献类型：
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作者：
Wang, Dingbowen;Xia, Tunan;Wang, Yuqi;Chen, Yizhu;Zhang, Chenji;Murray, William;Schultz, Adam Thomas;Liu, Zhiwen;Yang, Jian
卤化物在人类健康和环境监测中起着重要作用。然而，在当前的测量方法中，不同的卤化物相互干扰。以快速和低成本的方式同时感测多种卤化物仍然是一个挑战。在这里，我们报告了一种荧光多卤化物传感方法，通过使用一个单一的柠檬酸盐为基础的荧光团，CA-半胱氨酸，在定制的便携式设备。由于卤素离子的动态猝灭，CA-Cys发射的荧光被猝灭;灵敏度因卤化物类型和pH而异，从而能够在各种pH值下获得多个Stern-Volmer方程。每种卤化物的浓度然后可以通过求解得到的方程组来获得。一个mM规模的检测限证明，这是适合卤化物废水监测。一个基于智能手机的便携式设备的概念验证也制造和测试。从荧光计和便携式设备的结果表明，我们的多卤化物系统是有前途的现实世界的多卤化物传感应用。这项工作代表了一个新的方向，在发展便携式，低成本，同时多卤化物传感技术。
Halides play important roles in human health and environmental monitoring. However, different halides interfere with each other in current measurement methods. Simultaneous sensing of multiple halides in a fast and low-cost manner remains a challenge. Here, we report a fluorometric multi-halide sensing method by using a single citrate-based fluorophore, CA-Cys, on a custom-made portable device. The fluorescence emitted by CA-Cys is quenched due to the dynamic quenching of halide ions; the sensitivities vary from halide types and pH, providing the capability to obtain multiple Stern-Volmer equations at various pH values. The concentration of each halide can then be obtained by solving the resultant set of equations. A mM scale detection limit is demonstrated, which is suitable for halide wastewater monitoring. A proof-of-concept smartphone-based portable device is also fabricated and tested. The results from the fluorometer and portable device indicated that our multi-halide system is promising for real-world multi-halide sensing applications. This work represents a new direction in developing portable, low-cost, and simultaneous multi-halide sensing technologies.