Investigation of Hydrogenation of Toluene to Methylcyclohexane in a Trickle Bed Reactor by Low-Field Nuclear Magnetic Resonance Spectroscopy
Investigation of Hydrogenation of Toluene to Methylcyclohexane in a Trickle Bed Reactor by Low-Field Nuclear Magnetic Resonance Spectroscopy
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低场核磁共振波谱研究滴流床反应器中甲苯加氢制甲基环己烷
DOI：
10.1366/000370209789553156
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发表时间：
2009
影响因子：
3.5
通讯作者：
R. Reimert
中科院分区：
文献类型：
--
作者：
G. Guthausen;Agnes von Garnier;R. Reimert
利用低场核磁共振波谱研究了甲苯在实验室反应器中的加氢反应。对传统的台式核磁共振系统进行了改进，以实现化学位移解析。在对该方法进行离线有效性检验后，应用化学计量学数据处理，在过程中在线分析反应产物。将甲苯转化为甲基环己烷的转化率与离线气相色谱分析进行了比较。采用了经典的分析和化学计量学数据处理方法。由于在几十秒内获得的结果在两种方法的实验精度内相当，低场核磁共振光谱被证明为反应表征和即时反馈提供了一种分析工具。
Low-field nuclear magnetic resonance (NMR) spectroscopy is applied to study the hydrogenation of toluene in a lab-scale reactor. A conventional benchtop NMR system was modified to achieve chemical shift resolution. After an off-line validity check of the approach, the reaction product is analyzed on-line during the process, applying chemometric data processing. The conversion of toluene to methylcyclohexane is compared with off-line gas chromatographic analysis. Both classic analytical and chemometric data processing was applied. As the results, which are obtained within a few tens of seconds, are equivalent within the experimental accuracy of both methods, low-field NMR spectroscopy was shown to provide an analytical tool for reaction characterization and immediate feedback.