Biofunctionalization of nanoparticles for cytosensing and cell surface carbohydrate assay
Biofunctionalization of nanoparticles for cytosensing and cell surface carbohydrate assay
复制标题
用于细胞传感和细胞表面碳水化合物测定的纳米粒子的生物功能化
DOI：
10.1039/c1jm13700j
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发表时间：
2011-01-01
影响因子：
--
通讯作者：
Ju, Huangxian
中科院分区：
文献类型：
--
作者：
Ding, Lin;Ju, Huangxian
开发敏感和具体的传感策略来探测活细胞内/在活细胞内的化学和生物事件，最终可以有助于理解生命过程。这些策略也有利于疾病的早期诊断和早期成功的治疗。纳米粒子的生物功能化可以将生物成分和纳米粒子的优异性能结合在一起，从而为追踪识别和转导过程以及提高传感性能提供了一个有前途的平台。这篇专题文章综述了目前关于生物功能化策略的研究，以及生物纳米复合材料在细胞传感和细胞表面碳水化合物检测领域的应用。
Developing sensitive and specific sensing strategies for probing the chemical and biological events in/at a living cell can ultimately contribute to the understanding of life processes. These strategies are also beneficial to early diagnosis of diseases for early and successful treatment. Biofunctionalization of nanoparticles can integrate remarkable properties of both biological components and nanoparticles, thus providing a promising platform for tracing the recognition and transduction processes and improving the sensing performance. This Feature Article reviews the current research regarding the biofunctionalization strategies, and the usage of the bionanocomposites in the arena of cytosensing and cell surface carbohydrate assay.