A CASE-CONTROL STUDY OF COLORECTAL-CANCER AND ITS RELATION TO DIET, CIGARETTES, AND ALCOHOL-CONSUMPTION IN SAITAMA PREFECTURE, JAPAN
A CASE-CONTROL STUDY OF COLORECTAL-CANCER AND ITS RELATION TO DIET, CIGARETTES, AND ALCOHOL-CONSUMPTION IN SAITAMA PREFECTURE, JAPAN
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DOI：
10.1620/tjem.171.153
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发表时间：
1993-10-01
影响因子：
2.2
通讯作者：
SASABA, T
中科院分区：
文献类型：
--
作者：
HOSHIYAMA, Y;SEKINE, T;SASABA, T
在日本琦玉县进行了一项与饮食、吸烟和饮酒习惯有关的结直肠癌病例对照研究。该研究基于一个机构的181例新诊断的结直肠腺癌病例和653例普通人群对照。根据食物摄入频率问卷中的12种食物和12种食物组的摄入量以及个人食物偏好调查了饮食习惯。对咸味食物的偏好与结肠癌和直肠癌的风险呈正相关，而海藻的消费与这些癌症呈负相关，两者都具有剂量反应关系。吸烟与结肠癌风险呈负相关，但与直肠癌风险无关。酒精摄入量与结肠癌呈负相关，但与直肠癌无关。在多元逻辑回归中，对咸食物的偏好（正）和海藻的消费（负）与结肠癌和直肠癌的风险独立相关。
A case-control study of colorectal cancer in relation to dietary, smoking, and drinking habits was undertaken in Saitama Prefecture, Japan. The study was based on 181 newly diagnosed cases of adenocarcinoma of the colorectum at a single institution and 653 general population controls. Dietary habits were investigated on the basis of the intake of 12 foods and 12 food groups in a food intake frequency questionnaire, together with individual food preferences. Preference for salty foods was positively related to the risk of both colon and rectal cancer, and the consumption of seaweed was inversely related to these cancers, both with a dose-response relation. Cigarette smoking was inversely related to colon cancer risk, but not to rectal cancer risk. Alcohol intake tended to be associated inversely with colon cancer, but not with rectal cancer. In the multiple logistic regression, preference for salty foods (positively) and the consumption of seaweed (inversely) were independently related to both colon and rectal cancer risks.