Surgery-related Complications in 1253 Robot-assisted and 485 Open Retropubic Radical Prostatectomies at the Karolinska University Hospital, Sweden

Surgery-related Complications in 1253 Robot-assisted and 485 Open Retropubic Radical Prostatectomies at the Karolinska University Hospital, Sweden
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DOI:
10.1016/j.urology.2009.09.075
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发表时间:
2010-05-01
期刊:
影响因子:
2.1
通讯作者:
Wiklund, Peter N.
Wiklund, Peter N.
中科院分区:
医学4区
文献类型:
--
作者:
Carlsson, Stefan;Nilsson, Andreas E.;Wiklund, Peter N.

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量化在我们机构接受机器人辅助根治性膀胱切除术(RARP)和开放性耻骨后根治性膀胱切除术(RRP)治疗的患者的手术并发症。根治性前列腺切除术是与特定的并发症,可以影响结果的patient.METHODS之间的2002年1月和2007年8月,一系列的1738例连续患者进行RARP(n = 1253)或RRP(n = 485)的临床局限性前列腺癌。使用前瞻性医院并发症登记研究评估手术相关并发症。所有患者的基线特征均记录preoperations.Results总体而言,170例患者需要输血(9.7%),112例(23%)在RRP组与58例(4.8%)在RARP组。RRP组44例(9%)发生感染并发症,RARP组18例(1%)。22例(4.5%)接受RRP的患者接受了膀胱颈挛缩治疗,而RARP组为3例(0.2%)。Clavien IIIb-V级并发症在RRP患者中更常见(n = 63; 12.9%)(n = 46; 3.7%)。结论:在我们机构引入RARP导致Clavien IIIb-V级并发症(如膀胱颈挛缩)患者数量减少,需要输血的患者数量减少,减少术后伤口感染的患者数量。泌尿学75:1092-1099,2010年。(C)2010年爱思唯尔公司
OBJECTIVES To quantify complications to surgery in patients treated with robot-assisted radical prostatectomy (RARP) and open retropubic radical prostatectomy (RRP) at our institution. Radical prostatectomy is associated with specific complications that can affect outcome results in patients.METHODS Between January 2002 and August 2007, a series of 1738 consecutive patients underwent RARP (n = 1253) or RRP (n = 485) for clinically localized prostate cancer. Surgery-related complications were assessed using a prospective hospital-based complication registry. The baseline characteristics of all patients were documented preoperatively.RESULTS Overall, 170 patients required blood transfusions (9.7%), 112 patients (23%) in the RRP group compared with 58 patients (4.8%) in the RARP group. Infectious complications occurred in 44 RRP patients (9%) compared with 18 (1%) in the RARP group. Bladder neck contracture was treated in 22 (4.5%) patients who had undergone RRP compared with 3 (0.2%) in the RARP group. Clavien grade IIIb-V complications were more common in RRP patients (n = 63; 12.9%) than in RARP patients (n = 46; 3.7%).CONCLUSIONS The introduction of RARP at our institution has resulted in decreased number of patients with Clavien grade IIIb-V complications, such as bladder neck contractures, a decrease in the number of patients who require blood transfusions, and decreased numbers of patients with postoperative wound infections. UROLOGY 75: 1092-1099, 2010. (C) 2010 Elsevier Inc.