Nonverbal cognitive assessment of children in Tanzania with and without HIV.
Nonverbal cognitive assessment of children in Tanzania with and without HIV.
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DOI：
10.1080/09297049.2021.1957809
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发表时间：
2022-01
期刊：
影响因子：
--
通讯作者：
Buckey J
中科院分区：
文献类型：
--
作者：
Lichtenstein J;Bowers C;Amato J;Niemczak C;Fellows A;Magohe A;Haile H;White-Schwoch T;Kraus N;Massawe E;Moshi N;Buckey J
Children living with HIV can experience cognitive difficulties. Most neuropsychological tests have been constructed in Western languages, meaning they may not be appropriate for use in non-Western settings. To address this, we used an entirely nonverbal measure of cognitive ability in a sub-Saharan African sample. For this cross-sectional analysis, 316 children (162 HIV+ and 154 HIV−, ages 3-8) completed the Leiter-3 as part of a larger study in Dar es Salaam, Tanzania. Statistical tests included analysis of covariance and multiple linear regression to account for environmental variables. HIV+ children performed worse than HIV− controls on two composite scores: Nonverbal IQ (p < .001) and Processing Speed (p < 0.001). Similar trends were observed on core subtests. Multiple linear regression models revealed that age, socioeconomic status, and school attendance predicted all Leiter-3 test composites. Critically, the addition of HIV status to the models improved prediction of Nonverbal IQ (ΔR2 = 0.03, p = .001) and Processing Speed (ΔR2 = 0.06, p < .001). Children living with HIV performed worse than HIV− controls on most Leiter-3 measures. While age, SES, and school attendance predicted Leiter-3 performance, HIV status improved prediction capabilities when added to the model. The Leiter-3 may offer a viable measure of cognitive ability in non-Western settings that can be used in its original form without translation.
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