C2-symmetric bicyclo[2.2.2]octadienes as chiral ligands:: Their high performance in rhodium-catalyzed asymmetric arylation of N-tosylarylimines
C2-symmetric bicyclo[2.2.2]octadienes as chiral ligands:: Their high performance in rhodium-catalyzed asymmetric arylation of N-tosylarylimines
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DOI：
10.1021/ja044790e
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发表时间：
2004-10-27
影响因子：
15
通讯作者：
Hayashi, T
中科院分区：
文献类型：
--
作者：
Tokunaga, N;Otomaru, Y;Hayashi, T
利用一种新的C2对称二烯配体（1 R，4 R）-2，5-二苯基双环[2.2.2]辛-2，5-二烯（Ph-bod*），在铑催化下，通过N-甲苯磺酰基芳基亚胺与芳基环硼氧烷的不对称芳基化反应，实现了高对映选择性（95− 99%ee）的二芳基甲胺的不对称合成.
Asymmetric synthesis of diarylmethylamines with high enantioselectivity (95−99% ee) was realized by use of a newC2-symmetric diene ligand, (1R,4R)-2,5-diphenylbicyclo[2.2.2]octa-2,5-diene (Ph-bod*), for the rhodium-catalyzed asymmetric arylation ofN-tosylarylimines with arylboroxines.