Multifunctional monomer acts as co-initiator and crosslinker to provide autonomous strengthening with enhanced hydrolytic stability in dental adhesives
Multifunctional monomer acts as co-initiator and crosslinker to provide autonomous strengthening with enhanced hydrolytic stability in dental adhesives
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DOI：
10.1016/j.dental.2019.11.007
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发表时间：
2020-02-01
期刊：
影响因子：
5
通讯作者：
Spencer, Paulette
中科院分区：
文献类型：
--
作者：
Song, Linyong;Sarikaya, Rizacan;Spencer, Paulette
Objective.本研究的目的是评估一种新合成的多官能单体，氨基硅烷官能化的甲基丙烯酸酯（ASMA），含有可聚合的甲基丙烯酸酯，叔胺，和甲氧基硅烷官能度的牙科粘合剂配方，并研究聚合动力学，沥滤物，共聚物的热和机械性能。使用含有HEMA/BisGMA（45/55，w/w）的粘合剂作为对照，并且使用基于质量比为45/（55-x）/x的HEMA/BisGMA/ASMA的混合物作为实验粘合剂。粘合剂的特点是水溶性，光聚合行为（傅里叶变换红外光谱，FTIR），沥滤共聚单体（高效液相色谱，HPLC），热性能（调制差示扫描量热仪，MDSC），和机械性能（动态力学分析仪，DMA）。应力松弛时间和相应的模量，从应力松弛试验中得到的，用于模拟线性加载情况。与对照相比，含ASMA的粘合剂显示出更高的水溶性、更低的粘度、改进的单体至聚合物转化率、显著更大的Tg和橡胶模量。HPLC结果表明乙醇中浸出的HEMA（高达85重量%）和BisGMA（高达55重量%）显著减少。模拟结果表明，含ASMA的粘合剂比对照粘合剂的刚度大得多。ASMA单体具有多种作用，即它既可作为共引发剂又可作为交联剂，同时还可在粘合剂配方中提供自主增强和增强的水解稳定性。这种多功能单体为提高复合材料/牙齿界面粘合剂的耐久性提供了重要的希望。(C)2019年牙科材料学院。爱思唯尔公司出版All rights reserved.
Objective. The purpose of this study was to evaluate a new synthesized multifunctional monomer, aminosilane functionalized methacrylate (ASMA), containing polymerizable methacrylate, tertiary amine, and methoxysilane functionalities in dental adhesive formulations, and to investigate the polymerization kinetics, leachates, thermal and mechanical properties of copolymers.Methods. Adhesive contained HEMA/BisGMA (45/55, w/w) was used as a control, and mixtures based on HEMA/BisGMA/ASMA at the mass ratio of 45/(55-x)/x were used as experimental adhesive. Adhesives were characterized with regard to water miscibility, photo-polymerization behavior (Fourier transform infrared spectroscopy, FTIR), leached co-monomers (high performance liquid chromatography, HPLC), thermal properties (modulated differential scanning calorimeter, MDSC), and mechanical properties (dynamic mechanical analyzer, DMA). Stress relaxation times and the corresponding moduli, obtained from stress relaxation tests, are used in a simulated linear loading case.Results. As compared to the control, ASMA-containing adhesives showed higher water miscibility, lower viscosity, improved monomer-to-polymer conversion, significantly greater Tg and rubbery modulus. HPLC results indicated a substantial reduction of leached HEMA (up to 85 wt%) and BisGMA (up to 55 wt%) in ethanol. The simulation reveals that the ASMA-containing adhesive becomes substantially stiffer than the control.Significance. ASMA monomer plays multiple roles, i.e. it serves as both a co-initiator and crosslinker while also providing autonomous strengthening and enhanced hydrolytic stability in the adhesive formulations. This multifunctional monomer offers significant promise for improving the durability of the adhesive at the composite/tooth interface. (C) 2019 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved.