Auditory-nerve-fiber responses to high-level clicks: Interference patterns indicate that excitation is due to the combination of multiple drives
Auditory-nerve-fiber responses to high-level clicks: Interference patterns indicate that excitation is due to the combination of multiple drives
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DOI：
10.1121/1.428648
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发表时间：
2000-05-01
影响因子：
2.4
通讯作者：
Guinan, JJ
中科院分区：
文献类型：
--
作者：
Lin, T;Guinan, JJ
尽管点击在揭示系统的自然共振方面具有优势，但尚未有对高水平点击的神经纤维（ANF）反应的系统研究。使用高达120 dB pSPL的咔哒声研究猫单个ANF。针对不应效应校正响应的围刺激时间（PST）直方图，并从稀疏和凝聚点击PST形成复合PST（cPST）直方图。在低水平下，响应遵循经典的图片，每个cPST似乎是从一个单一的谐振系统，然后低通滤波，减少高频同步。在所有特征频率的纤维中，在高点击水平下存在显着不同的模式，包括几个非经典特征和“相位反转”，即，在低电平处的稀疏-点击PST中的峰值在高电平处被在凝聚-点击PST中的相同等待时间处的峰值替代。有两个独立的区域的非经典功能和相位反转，这表明，耳蜗神经纤维兴奋的组合在某些阶段在耳蜗中的至少三个激励驱动器来自声刺激。这些数据支持这样的解释，即耳蜗分区以多个共振模式振动，每个模式产生一个激励驱动，并且模式的混合随声级而变化。(C)2000年美国声学学会。【S0001-4966（00）00205-8】。
There has been no systematic study of auditory-nerve-fiber (ANF) responses to high-level clicks despite the advantages of clicks in revealing the natural resonances of a system. Cat single ANFs were studied using clicks up to 120 dB pSPL. Peri-stimulus-time (PST) histograms of responses were corrected for refractory effects, and compound PST (cPST) histograms were formed from rarefaction- and condensation-click PSTs. At low levels the responses followed the classic picture with each cPST appearing to be from a single resonant system followed by low-pass filtering that reduces high-frequency synchrony. In fibers across all characteristic frequencies, there were significantly different patterns at high click levels including several nonclassic features and "phase reversals," i.e., a peak in the rarefaction-click PST at low levels was replaced at high levels by a peak at the same latency in the condensation-click PST. There were two separate regions of nonclassic features and phase reversals, which indicates that auditory-nerve fibers are excited by the combination at some stage in the cochlea of at least three excitation drives derived from the acoustic stimulus. These data support the interpretation that the cochlear partition vibrates in multiple resonant modes with each mode producing one excitation drive and that the mix of modes varies with sound level. (C) 2000 Acoustical Society of America. [S0001-4966(00)00205-8].