Completely resolved advanced biliary tract cancer after treatment by pembrolizumab: a report of two cases

Completely resolved advanced biliary tract cancer after treatment by pembrolizumab: a report of two cases
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DOI:
10.2147/ott.s197559
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发表时间:
2019-01-01
影响因子:
4
通讯作者:
Obeidat, Khaled A.
Obeidat, Khaled A.
中科院分区:
医学3区
文献类型:
--
作者:
Alshari, Osama M.;Dawaymeh, Tamara A.;Obeidat, Khaled A.

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胆道癌(BTC)是一种侵袭性疾病,预后差.吉西他滨联合顺铂是晚期BTC的标准一线姑息治疗。吉西他滨-顺铂治疗进展后尚无既定治疗。在这篇文章中,我们介绍了两例晚期BTC患者,他们接受了pembrolizumab治疗,肿瘤已经完全消退。
Biliary tract cancers (BTC) represent an aggressive disease with a dismal prognosis. Gemcitabine in combination with cisplatin is the standard first-line palliative treatment for advanced BTC. There is no established treatment following progression on gemcitabine-cisplatin. In this article, we present two cases for individuals with advanced BTC who were treated with pembrolizumab and the tumors have completely resolved.