Pseudomonas aeruginosa Biofilm Inactivation: Decreased Cell Culturability, Adhesiveness to Surfaces, and Biofilm Thickness Upon High-Pressure Nonthermal Plasma Treatment.
Pseudomonas aeruginosa Biofilm Inactivation: Decreased Cell Culturability, Adhesiveness to Surfaces, and Biofilm Thickness Upon High-Pressure Nonthermal Plasma Treatment.
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铜绿假单胞菌生物膜失活：高压非热等离子体处理后细胞培养性、表面粘附性和生物膜厚度降低。
DOI：
10.1109/tps.2010.2082570
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Brelles-Mariño,Graciela
中科院分区：
文献类型：
--
作者：
Zelaya,AnnaJ;Stough,Gregory;Rad,Navid;Vandervoort,Kurt;Brelles-Mariño,Graciela
细菌生物膜比自由生活的细菌更能适应标准的杀灭方法。铜绿假单胞菌PAO1生物膜上生长的硼硅酸盐试样进行了处理与气体放电等离子体的各种曝光时间。在5分钟的血浆暴露后，几乎100%的细胞被灭活。原子力显微镜被用来成像的生物膜，并研究其微观力学性能。结果表明，经等离子体处理后，假单胞菌生物膜的厚度和硼硅酸盐的含量降低。
Bacterial biofilms are more resilient to standard killing methods than free-living bacteria. Pseudomonas aeruginosa PAO1 biofilms grown on borosilicate coupons were treated with gas-discharge plasma for various exposure times. Almost 100% of the cells were inactivated after a 5-min plasma exposure. Atomic force microscopy was used to image the biofilms and study their micromechanical properties. Results show that the adhesiveness to borosilicate and the thickness of the Pseudomonas biofilms are reduced upon plasma treatment.