Recurrence of Escherichia coli meningitis in a preterm infant and co-infection of echovirus 18.
Recurrence of Escherichia coli meningitis in a preterm infant and co-infection of echovirus 18.
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作者：
Kato K;Mizumoto H;Matsubara K;Hata A;Wachino JI;Arakawa Y;Hata D
细菌性脑膜炎在适当的抗生素治疗后可能复发。然而，在大多数情况下，病理生理不能确定。我们描述了一个早产儿，由于在出生时和在3周适当抗生素治疗结束后10天感染相同的大肠杆菌菌株而反复发作脑膜炎。复发时，患者表现为急性心肌炎引起的暴发性严重心力衰竭，并发埃可病毒18感染（通过粪便培养和血清学分析证实）。埃可病毒合并感染可能是本例大肠杆菌脑膜炎复发的原因。
Bacterial meningitis may relapse after adequate antibiotic treatment. In most cases, however, the pathophysiology cannot be identified. We describe a preterm infant with recurrent episodes of meningitis due to infection with an identical Escherichia coli strain both at birth and at 10 days after cessation of a 3 week course of appropriate antibiotic treatment. At the time of recurrence, the patient presented with fulminant severe cardiac failure due to acute myocarditis, coupled with a concurrent echovirus 18 infection (confirmed by stool culture and serological analysis). Co-infection by echovirus may underlie recurrence of Escherichia coli meningitis in this case.