Antibody to p40tax protein of human T cell leukemia virus 1 and infectivity.
Antibody to p40tax protein of human T cell leukemia virus 1 and infectivity.
复制标题
人T细胞白血病病毒1型p40tax蛋白抗体及其感染性。
DOI：
--
复制
发表时间：
1990
影响因子：
6.4
通讯作者：
A. Koide
中科院分区：
文献类型：
--
作者：
S. Kashiwagi;W. Kajiyama;J. Hayashi;A. Noguchi;K. Nakashima;H. Nomura;H. Ikematsu;T. Sawada;S. Kida;A. Koide
To investigate the physiologic significance of antibody to human T cell leukemia virus type 1 (HTLV-1) tax gene product (p40tax), 147 male and 243 female HTLV-1 carriers were examined for anti-p40tax, and 104 carriers were checked for anti-p40tax an average of 5.4 times during an 8-year period. Prevalence of anti-p40tax was significantly higher in female (62.6%) than in male subjects (51.0%; P less than .05). Anti-p40tax status did not change in most during the observation period. There were significantly more HTLV-1 carriers among children of anti-p40tax-positive mothers (45.3%) than among those from anti-p40tax-negative mothers (20.0%; P less than .01). However, no significant difference was observed between wives of p40tax-positive and -negative men. The p40tax antibody may be a marker of relative infectivity of HTLV-1, albeit an imperfect one.
