A Prospective Study of Health Symptoms And Aspergillus fumigatus Spore Counts Near a Grass and Leaf Composting Facility
A Prospective Study of Health Symptoms And Aspergillus fumigatus Spore Counts Near a Grass and Leaf Composting Facility
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草叶堆肥设施附近健康症状和烟曲霉孢子计数的前瞻性研究
DOI：
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发表时间：
2001
期刊：
影响因子：
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通讯作者：
Edward G. Horn
中科院分区：
文献类型：
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作者：
M. Browne;C. L. Ju;G. Recer;L. Kallenbach;J. Melius;Edward G. Horn
烟曲霉（曲霉）是一种在堆肥中发现的真菌，是一种呼吸道过敏原，可在易感个体中引起严重的侵袭性疾病。我们在一个40英亩的草叶堆肥设施附近进行了一项研究，包括收集健康症状数据和环境监测数据。分析基于来自研究区63名个体和来自参考区82名个体的症状日记数据。空气传播的烟曲霉与呼吸道或刺激性症状的增加无关。自研究开始以来，症状发生率与豚草、臭氧、温度和时间有关，尽管随着研究的进展，报告的症状减少的趋势可能使这一结果混淆。研究设计的其他特点包括短期孢子数变异性、缺乏个体暴露数据和症状日记数据的空白、对结果的复杂解释。虽然本研究不支持过敏和哮喘症状发生率与烟曲霉孢子水平之间的关联，但我们无法评估非常敏感的个体中异常但严重疾病的风险。
Aspergillus fumigatus (A. fumigatus), a fungus found in compost, is a respiratory allergen and can cause serious invasive disease in susceptible individuals. We conducted a study involving the collection of health symptom data and environmental monitoring data near a 40-acre grass and leaf composting facility. Analyses were based on symptom diary data from 63 individuals from the study area and 82 individuals from a reference area. Airborne A. fumigatus was not associated with increases in respiratory or irritative symptoms. Symptom incidence was associated with ragweed, ozone, temperature, and time since start of the study, although a tendency to report fewer symptoms as the study progressed may have confounded this result. Other features of the study design, including short-term spore count variability, lack of individual exposure data and gaps in the symptom diary data, complicated interpretation of the results. Although this study does not support an association between allergy and asthma symptom incidence and A. fumigatus spore levels, we could not assess the risk of unusual, but severe illnesses among very sensitive individuals.
DOI：
10.1164/ajrccm/144.3_pt_1.668
发表时间：
1991-09-01
期刊：
AMERICAN REVIEW OF RESPIRATORY DISEASE
影响因子：
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作者：
POPE, CA;DOCKERY, DW;RAIZENNE, ME
通讯作者：
RAIZENNE, ME